Medication Administration
What method is considered least effective and requires longer periods of time to have an impact
Topical application
This is the range of drug concentrations in the blood that are effective but not toxic.
What is the therapeutic window?
What test is used to test the smallest amount of the drug that will INHIBIT GROWTH of the pathogen?
MINIMUM INHIBITORY CONCENTRATION (MIC) TEST
What is one pro of narrow spectrum drugs?
When the specific problem is identified, it can be treated easily without affecting the rest of the body.
This is the mechanism by which a microbe actively expels the antimicrobial drug from inside itself
Pump
What method is used to treat the infection directly at the site, and does not stay in circulation for much time
Intramuscular injection (administration)
This ratio compares the toxic dose of a drug to its effective dose and tells us how safe the drug is.
What is the therapeutic index?
What test is used to test the smallest amount of the drug that will kill the microbe?
MINIMUM BACTERICIDAL CONCENTRATION (MBC) TEST
What is one con of broad spectrum drugs?
It can disrupt the body’s normal microbial balance, allowing unrelated infections to develop.
This is the mechanism by which a group of various microbes create a community with an extracellular matrix in order to resist an antimicrobial drug
Biofilm
_____ administration is most effective and lasts for as long as administered
Intravenous Administration
A drug with a high therapeutic index is _______ than a drug with a low therapeutic index
What is safer?
What test uses Zones of inhibition to see where bacteria do not grow, and therefore finds the most effective drug?
DIFFUSION SUSCEPTIBILITY TEST
What is one pro of broad-spectrum drugs?
if the exact illness isn’t identified, it may address the problem
This is the most common way that drug-resistance genes are shared between Bacteria
Horizontal Gene Transfer by Conjugation