When neutrophils attempt to cover uric acid crystals, this process can lead to the explosion of the cell and the release of web DNA and enzymes, amplifying joint inflammation.
netosis
madre by the inflammasomee, this cytokine drives the intense pain, redness, and swelling of a gout attack.
interleukin 1-beta
This cell complex acts as a sensor within macrophages, detecting the phagocytosed crystals and causing the initial inflammatory result.
NLRP3 imflamesome
As the main first res ponders of the innate immune system, these blood cells are made to the joint in big numbers to cover the crystals.
Neutrophils
pin-shaped crystals, which form when blood uric acid levels are too big, act as the main "antigen" that causes the immune system's alarm in gout.
uric acid crystals