Basic Pharm
What kind of interactions can happen?
-drug/alternative therapy (OTC St. Johns Wart)
-Drug/laboratory (drugs changing lab values giving false positives)
-drug/food (grapefruit juice)
Beta cells do what?
secreting insulin to help bring down blood sugar
what medication do you want to hold for 24 hours is they are getting a test with iodine?
Metfromin
what does the thyroid hormone do?
regulates metabolism, heat production, body temperature, cardiac output
what is Pharmacokinetics? And what processes are involved?
-how the body changes the drug
-Absorption, Distrubtion, Metabolism, Elimination
what is peak?
highest point of your medication action
alpha cells do what?
help to release the stored glucose in your liver to bring the blood sugar back up
releases hormone to help bring glucose to your blood
alpha cells will respond to the need of sugar by releasing it's hormone
Name a rapid acting insulin? What is the onset, peak, duration?
-Apidra, Novolog, Humalog
-onset - 5-15 min
-peak - 30 min -1.5 hour
-duration - 3-5 hour
Symptoms of hypothyroid?
obesity - weight gain, lethargic/fatigue, bradycardia, pale, loss of hair, intolerance to cold, decreased body temperature, goiter
3 spaces a drug can be distributed to?
Cell, interstitial space and blood vessel
what is trough?
lowest point of your medication action
Name the three P's?
Polyuria
Polydipsia
Polyphagia
-ends in "R" - Novolin R, Humulin R
-onset - 30 min
-peak - 2.5 - 5 hours
-duration - 6-8 hours
use with meals, correctional insulin, sliding scale
symptoms of hyperthyroid?
What is Pharmacodynamics?
how we are affected by the drug
what are the 8 rights?
1. Right patient 2. Right medication 3. Right Route 4. Right Dosage 5. Right time
6. Right Documentation 7. Right diagnosis
8. Right response
Insulin secretaogues?
work by stimulating the beta cell to make insulin. need to have a functioning beta cell
Name a long lasting insulin? What is the onset, peak, duration?
-onset - 2 hour
-peak - no peak time
-duration - 24 hour
Which problem is an adverse effect of levothyroxine (synthroid)?
A. obesity B. Heart Failure C. Type 2 DM D. Venous thromboembolism
B. Heart failure
What is idiosyncratic effects?
Unusual side effect to you
individualized
when getting a verbal order you need?
insulin sensitizers?
What is a NPH -Intermediate acting insulin? what is the onset, peak and duration?
-onset- 1.5 hours
-peak - 4-12 hours
-duration - 10-16 hours
why are the effects of methimazole (tapazole) delayed for the first 3 weeks?
body stores T3 & T4 for 2-3 weeks so effect may not start till reserves are depleted. The drug has no effect on stored thyroid hormone