HIV drugs
DM drugs
*BONUS*
Antivirals
Antimicrobials
100

Nevirapine is what class of drug?

Non-nucleoside reverse transcriptase inhibitor (NNRTI)

100

Which Insulin preparation would you give to a child with DKA?

Short acting "Regular" insulin (IV)

100

Which Thioamide is known to cause Hepatotoxicity ?

Propylthiouracil (PTU)

100

Which enzyme does Zanamivir inhibit?

Viral Neuraminidase 

100

Give one M.O.A of the disinfectants: Alcohol and Chlorhexidine?

*Denature proteins*

*Distrupt cell membrane*

200

What HIV gene codes for HIV-1 PROTEASE ?

pol gene

200

Which mitochondrial enzyme does Biguanides(metformin) inhibit?

mitochondrial Glycero-Phosphate Dehydrogenase (mGPD)

200

M.O.A of Esomeprazole?

Irreversibly inhibits H+/K+ ATPase (parietal cells)

200

What cell(s) does Maraviroc bind to?

Monocytes /T cells (CCR5)
200

M.O.A of Lindane

Blocks GABA channels

300

Which nucleoside reverse transcriptase inhibitor (NRTI) is known to cause anemia? 

Zidovuidine(ZDV)="AZT"


300

Which DM drug is known to cause "orthostatic hypotension"

Sodium glucose co-transporter2 (SGLT2) inhibitors

300

Which enzyme does methimazole inhibit?

Thyroid peroxidase

300

Which drug would you use for herpez soster(shingles)?

Famciclovir 

300

Permethrin M.O.A ?

Inhibits Na+ channel deactivation

400

What HLA subtype is cotraindicated in Abacavir(ABC) due to hypersensitivity reactions?

HLA-B*5701

400
Which class of DM drug is known to predispose patients to respiratory infections?

DDP-4 inhibitors 


400

name the drug that inhibits gastric and pancreatic LIPASE?

Orlistat 

400

Which drug has the following M.O.A

1. Viral DNA polymerase inhibitor

2. Viral RNA polymerase inhibitor

3. HIV reverse transcriptase inhibitor

Foscarnet 

400

M.O.A of action of Malathion?

Inhibits AChE

500

What HIV drug can cause 'vivid dreams'

Efavirenz

500
Which hormone is upregulated after the administration of Thiazolidinediones(glitazones)? 

Adiponectin

500

Which laxative is known to cause melanosis coli (darkened coloration of the colon)

Senna (stimulant) laxative 

500

What do NRTI's lack that causes DNA chain termination?

3' OH groups

500

2 Drugs used to treat Trypanasoma cruzi?

Benznidazole & Nifurtimox

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