Immune Cells
Viral Crimes
Influenza
Polio
History
100

Which cell does not use a perforin "gun" to kill cells?

a) NK      b) killer T

c) helper T

c) helper T

100
Which cell is guilty of identity theft, and invades T cells?

a) Adenovirus     b) HIV

c) Herpes        d) polio


b) HIV

100

How many segments are in its genome?

a) 1      b) 2

c) 4       d) 8

d) 8

100

Polio has an IRES.  What is the IRES made of?

a) proteins       b) glycoproteins

c) RNA      d) DNA

c) RNA

100

Which came first, the electron microscope or the PCR test?

electron microscope

200

What does "macrophage" mean?

a) big eater    b) big cell

c) virus eater    d) bacteria eater

a) big eater

200

True or False?  All viruses hi-jack the motor protein transport system to get things moved around.

True

200

Hair-pinning is a process that influenza uses during:

a) attachment    b) entry

c) replication       d) exit

b) entry

200
Where does the polio virus first enter the body?


a) skin      b) gut

c) nerve cells    d) lungs


b) gut

200

Which of these was the first test to be used to detect the presence of viruses?

a) plaque assay      b) PCR

c) electron microscopy     d) hemagglutination

a) plaque assay

300

Which of these is NOT a virus sensor?

a) TLR3       b) IFN

c) RIG-1     d) MDA5

b) IFN  (abbreviation for interferon)

300

What virus uses mutations in its capsid protein to confuse the immune cells and make it hard for them to recognize it?

a) adenovirus      b) polio

c) HIV     d) influenza

b) polio

300

Where does influenza replicate its genome?

a) cytosol     b) nucleus

c) ribosomes     d) ER

b) nucleus

300

What type of genome does polio have?

a) RNA (+)     b) RNA (-)

c) dsDNA      d) dsRNA

a) RNA (+)

300
True or False?

Jonas Salk was the only person to invent a vaccine for polio.


False.  Albert Sabin came up with another vaccine.

400

Which of these is NOT part of the innate (non-specific) immune system?

a) B cells      c) NK cells

b) physical barriers    d) sensors

a) B cells

400

Who is famous for "cap-snatching"?

a) polio    b) HIV

c) influenza    d) herpes

c) influenza

400

What type of genome does influenza have?

a) dsDNA      b) RNA (+)

c) RNA (-)     d) dsRNA

c) RNA (-)

400

Does polio virus have an envelope?

a) yes     b) no

b) no

400

Which of these viruses has been eliminated entirely as far as we know?

a) polio      b) chickenpox

c) measles      d) smallpox

d) smallpox

500

Which cell eats anything tagged with antibodies?

a) T cells     b) B cells

c) NK cells     d) macrophages

d) macrophages

500
Which virus makes proteins that look almost identical to interferon?

a) smallpox      b) chickenpox

b) polio          d) influenza


a) smallpox

500

Which of influenza's proteins acts like a scissor?

a) neuraminidase     b) NS1

b) hemagglutinin     d) NEP

a) neuraminidase

500

What does polio steal from cells and use as a construction material for its replication sites?

a) MHC-1       b) RIG-1

c) interferon      d) TLR-3

d) TLR-3

500
Why did doctors stop using phage therapy?

a) the invention of antibiotic pills

b) better prevention of bacterial infections

c) new bacteria that were immune to phages


a) the invention of antibiotic pills

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