1
Physiological effects of histamine include the following except..
systemic vasodilation
increased cardiac contractility
severe broncoconstricctions
increased vascular permeabilty
Increased cardiac contractility.
Once you have performed interventions what should you do?
recheck them
1326
absorption
As time and condition allow what should you perform?
Physical exam
1324
Which symptoms are first to show in anaphylaxis?
skin signs
1327
primary allergic reaction antibody
IgE
Extreme systemic form of allergic reaction
anaphylaxis
What site does benadryl work on and what is the MOA?
H1 by blocking the histamine effects
1330
These individuals have a higher incidence of anaphylaxis to latex, ASA, and muscle relaxers.
Women
1318
An antigen is most accurately defined as
A substance that causes the immune system to produce antibodies.
during this response macrophages confront and engulf
primary response
1320
3 GI symptoms in anaphylaxis
bloating, vomiting, diarrhea, nausea, distension
1327
What is the dosage in an adult epi pen
.30 mg
1329
Can histamine release cause dysrhthmias?
Yes, due to hypo perfusion and hypoxia
1326
This response occurs with a reexposure?
secondary response
1320
Ped dose for an epi pen or epi pen Jr?
0.15 mg
1329
How does histamine release affect CV output?
hypotension
vascular permeability
edema
fluid secretion and fluid loss
1326
what produce the bodies chemical mediators for immune response?
basophils and mast cells
1320
First line med for anaphylaxis with no difficulty breathing?
Benadryl
1328
Pt's with _______ are at an increased risk for anaphylaxis?
Atopic dermatitis
What is SLE?
Multi system autoimmune disease that occurs more commonly in women than in men. African american women are 4 times more likely to have this disease.
1331
How many types of shock does a pt in anaphylaxis experience?
1327
What types of shock can a pt experiencing anaphylaxis present with?
cardiogenic
hypovolemic
neurogenic
1327
If an antigen invades the body and combines with an antibody on this cells surface degranulation occurs?
Mast Cell
1320
Mechanism of action when Histamine is released?
local vessels to dilate
capillaries leak
1326