Blood Composition
Blood is the only type of what tissue in the body?
Fluid
Normal pH?
7.35-7.45
Diameter of RBC? Shape?
Small Diameter, Biconcave shape
Hematopoiesis? Where is it found?
Blood cell formation in red bone marrow
Axial skeleton, Girdles, Proximal Epiphyses of humerus, Femur
What is released by the kidneys?
EPO (Erythropoietin)
Matrix that is nonliving and fluid?
Plasma
What are the 3 main functions of Blood?
Transport, Regulation, Protection
Main components of Rbc?
Water, Hemoglobin
What is a hemocytoblast and what does it become?
Hematopoietic Stem Cells, any type of formed elements.
What is the general "basis" surrounding the kidneys?
if the kidneys have enough O2, the body does
Formed Elements?
Erythrocytes, Leukocytes, Platelets
What is Transported by blood?
O2, Metabolic wastes, Hormones
What is the number one Function?
Gas Transport
How long does the process of hemocytoblast to formed element take?
~ 15 days
Describe 1 & 2 of Homeostasis imbalance
1- stimulus: hypoxia
2- Kidney/Liver release EPO
All blood in the body is contained where?
Vessels
What is the role of Regulation?
Body Temp, pH, adequate fluid volume
Oxygen rich vs Oxygen poor? Co2 at tissue level?
Oxygen Rich- scarlet/ruby (Oxyhemoglobin)
Oxygen poor- dark red (deOxyhemoglobin)
Carbaminohemoglobin
How many days does a RBC live?
100-120 days
Describe 3,4,5
3- EPO stimulates red bone marrow
4-enhanced EPO increases RBC count
5-O2 carrying ability rises (hypoxic conditions stop)
Percent's of whole blood?
Plasma 55%
Erythrocytes 45%
Buffy coat <1%
What role does protection play?
Prevents Blood Loss, Infections
How many RBC in one drop of blood?
30 Mil
What is the result of too few RBC?
Too many?
Tissue Hypoxia
Increased blood viscosity
Causes of Kidney Hypoxia?
Insufficient number RBC
Reduced oxygenation of blood
increased aerobic demands
treatments