Cell Cycle
The copy of DNA is synthesized
S or Synthesis
Chemical signals regulate
the cell cycle
Messages from within the cell that direct the cell cycle
Internal signals
permanent damage to the DNA changing the normal expression of the gene
mutation
Formation of new blood vessels which feed the tumor
Angiogenesis
The cell grows, matures, and carries out its normal functions
G1 or 1st Growth
A chemical signal that comes from outside the cell
external signal
Regulate Progression through the Cell Cycle
Check points
Stop Division if DNA is Damaged
Normal
The process by which cancer spreads from the original tumor to other locations
Metastasis
The cell prepares for cellular division
G2 or 2nd Growth
Tissue damage and cell death will signal cells to
start cell division
Programmed Cell Self-Destruction
Apoptosis
Divide without signals
Cancer Cells
The cell's nucleus divides
M or Mitosis
Density dependent inhibition will signal cell
to stop cell division
Die after 50 Divisions
Normal Cells
Exhibit Density Dependent Inhibition
Normal Cells