Mitigare
When was Mitigare launched
2015
What are the side effects of Pazeo
blurred vision, dry eye, superficial punctate keratitis (an eye disorder caused by death of small groups of cells on the surface of the cornea), dysgeusia and abnormal sensation
What ingredient in TobraDexST suspension is designed to enhance the bioavailability of the active ingredients to the ocular surface?
With a typical heroin overdoes, bystanders may have up to 1 - 3 hours to review the patients. with synthetic opioid overdoses, the overdose can set in within _______
minutes
What is the timing of Zerviate's rapid onset of effect
3 minutes
What is the difference between Mitigare and the AG?
nothing, same capsule
What are the side effects of Bepreve
mild taste following instillation, eye irritation, headache and nasopharyngitis (nasal swelling or a cold)
What is the recommended dosing of TobraDexST
to instill one drop into the conjunctival sac(s) every 4-6 hours
67% of opioid-involved overdose deaths are attributed to _______
Fentanyl
A higher incidence of dry eye has been reported in patients using certain topical and systemic medication, including antihistamines. How many subjects reported dry eye as an adverse event in the Zerviate clinical trials?
1
maintenance doses of colchicine generally should be given prophylactically when ______ is begun
allopurinol
What is the dosing for Pataday / Pazeo
QD
In the suspension testing experiments, after 24 hours, TobraDexST demonstrated a settling rate of what percentage?
3%
Fentanyl is 50 -100 x stronger than _______
Morphine
Of the most commonly reported Zerviate side effects , how many patients experienced instillation site pain
3.9% which was considered mild in all cases
Name the three main urate lowering therapies
allopurinol, Uloric and Krystexxa
What is the dosing for Bepreve
BID
What is the most commonly observed symptom of viral and bacterial acute conjunctivitis?
Redness
From 2015 to 2020, what % of events required equal or greater than 2 doses of nalaxone by EMS
54%
___________ similar to the natural tear film means added comfort and tolerability
Neutral pH
When prescribing Mitigare, what is the best way to do so in EMR
Mitigare>DAW>pharmacy notes add: capsules only and add the universal copay card
What is the dosing for Lastacraft
QD
Tobramycin's MOA is considered to be _________ and ________
Bacteriostatic and Concentration-dependent bactericidal
What are the two resources that state...No unexpected or life-threatening events were reported in 4 - 16mg doses of nalaxone nasal spray in one 2016 survey of community distribution groups
Avetian et al 2018 and FDA Advisory Committee Meeting
Hydroxypropyl methylcellulose (HPMC), ingredients commonly found in _________
lubricant drops