MCQ-1
MCQ-2
MCQ-3
MCQ-4
100
Which intestinal cells produce antibacterial compounds?
A. Enterocytes
B. Enteroendocrine cells
C. Goblet cells
D. Microfold cells
E. Paneth cells
E. Paneth cells
100
Which description is true of pancreatic zymogens?
a. Are packaged for secretion in the SER
b. Are synthesized on free ribosomes
c. Are inactive until they reach the duodenal lumen
d. Are stored in the basal cytoplasm of acinar cells
e. Are produced by cuboidal cells lining the pancreatic duct
c. Are inactive until they reach the duodenal lumen
100
A first-year medical student seeks help to identify lymphoid follicles. She pulls out a slide that, in addition to abundant aggregation of lymphoid follicles, demonstrates prominent villi. Which of the following structures might she also be able to identify using the same slide?
A. Submucosal glands
B. Plicae circularis
C. Epiploic appendages
D. Tenia coli
E. Oxyntic cells
B. Plicae circularis
100
Which one of the following structures is responsible for basophilia in pancreatic acinar cells?
a. Golgi apparatus
b. Zymogen granules
c. Smooth endoplasmic reticulum
d. Rough endoplasmic reticulum
e.Glycogen granules
d. rough endoplasmic reticulum
200
An intestinal villus is examined at high magnification. In which of the following layers could macrophages and lymphocytes be visible in this slide specimen?
a. Epithelium of mucosa
b. Lamina propria
c. Muscularis externa
d. Muscularis mucosae
e. Submucosa
b. Lamina propria
200
The organ identified in image is examined at high magnification. Which of the following terms describes the glandular epithelial cells shown in the image?
a. Endocrine
b. Goblet
c. Mucous
d. Paracrine
e. Serous
e. Serous
200
Which of the following is true about Brunner’s glands?
a. Present throughout the small intestine
b. Present in the lamina propria
c. Secrete mucous rich in bicarbonate
d. Covered by epithelium containing M cells
e. Opens in the 2nd part of duodenum
c. Secrete mucous rich in bicarbonate
200
A silver stain is used to identify enteroendocrine cells in the pyloric region of the stomach (small dark stained cells) these cells are classified as open or closed. What is the primary function of open enteroendocrine cells in the GI tract?
a. Antibody secretion
b. Antigen uptake
c. Chemoreception
d. Gastrin secretion
e. Histamine release
c. Chemoreception
300
Which of the following statements concerning the histological structure of the organ in the figure is correct?
A. The mucosal lining is composed of simple squamous cells.
B. Goblet cells form the largest proportion of the mucosal cells.
C. Villi significantly increase the mucosal surface area.
D. Glands traverse less than half the thickness of the mucosa.
E. Longitudinal muscle fibers are absent in the wall.
C. Villi significantly increase the mucosal surface area.
300
A biopsy obtained from an area revealed simple columnar cells lining, deep pits consisting of mucus-secreting cells, and well-defined layers of smooth muscles. A smaller portion of the slide revealed goblet cells, villi, and submucosal glands. Which is the most likely segment of the GI that is being examined?
A. Gastroesophageal junction
B. Pectinate line
C. Gastroduodenal junction
D. Pharyngo-esophageal junction
E. Vermilion zone of lips
C. Gastroduodenal junction
300
The cells indicated by the arrows secrete which of the following substances?
a. Bicarbonate
b. Protease
c. Lysozyme
d. Gastrin
e. Pepsinogen
c. Lysozyme
300
Examination of the lamina propria of the organ identified in the photo reveals which of the following key histologic features of the GI tract?
a. Brunner glands
b. Lacteals
c. Meissner plexuses
d. Myenteric plexuses
e. Pyloric glands
b. Lacteals
400
Which of the following is an essential secretory product of the submucosal glands identified in the image?
a. Amylase
b. Bicarbonate ions
c. Hydrochloric acid
d. Lipase
e. Pepsinogen
(B) Bicarbonate ions
400
On a routine busy day in the laboratory, the technician forgets to label a biopsy specimen obtained from a 25-year-old woman. To make a diagnosis, the pathologist points to a prominent structure at the center of the field in the image. Which of the following is true for structure indicated (4)?
A. Drain into the floor of the mouth.
B. Drain in the cheek mucosa opposite the 2nd upper molar tooth.
C. Drain into the second part of the duodenum.
D. Drain into the inferior vena cava.
E. Drain into the hepatic portal vein
Drain in the cheek mucosa opposite the 2nd upper molar tooth.
400
During the seminar, you are asked to discuss the cellular mechanisms that mediate antibody transport across the epithelial barrier of the GI tract. Which of the following cells transports IgA from the lamina propria of the mucosa to the lumen of the gut?
a. Enterocytes
b. Goblet cells
c. Microfold cells
d. Paneth cells
e. Plasma cells
a. Enterocytes
400
Various GI organs are examined at a multiheaded microscope in the pathology department. You were asked to comment on the glandular shown in the image. These mucosal glands empty into which of the following segments of the GI tract?
a. Colon
b. Duodenum
c. Ileum
d. Jejunum
e. Stomach
e. Stomach
500
Which of the following is true about M cells? They
a. Are epithelial cells that cover only Payer’s patches
b. Have smooth apical surface by EM
c. Transfer intact Ag in endocytic vesicles
d. Transport processed Ag to lymphocytes
e. Have no surface receptors
Transfer intact Ag in endocytic vesicles
500
A 35-year-old complains of bloating, cramping abdominal pain, diarrhea with excessive flatulence after milk ingestion. In this disorder, the area shown by arrows would most likely have a decrease in which one of the following?
a. Specific disaccharidase activity
b. Glucose/galactose transporter activity
c. Passive diffusion of monosaccharides
d. Uptake of triglycerides by endocytosis
e. Active transport of glycerol
a. Specific disaccharidase activity
500
Which of the following features are present in the small bowel?
a. Villi are seen macroscopically as large folds arranged circularly around the lumen
b. Enterocytes have a well-developed macrovilli forming the brush border
c. Paneth cells are vacuolated, pale-staining cells in the neck region of intestinal Crypts
d. Brunner’s glands are serous glands found in the duodenum
e. All mucosal epithelial cells are derived from stem cells located in the crypt
e. All mucosal epithelial cells are derived from stem cells located in the crypt
500
A 45-year-old woman with a mass affecting the head of the pancreas. She was treated with a partial pancreatico-duodenectomy. The biopsy obtained from the surgical specimen is examined. Which of the following is true regarding structure indicated by the arrow?
A. Produces bile
B. Removes Na+ from pancreatic exocrine secretion
C. Secretes insulin
D. Secretes enzymes for protein digestion
E. Adds HCO3 to pancreatic exocrine secretion
E. Adds HCO3 to pancreatic exocrine secretion