ATA Guidelines
A Stim Tg test using rhTSH has almost what percent likelihood of identifying patients free of disease, provided they do not have anti Tg antibodies.
What is 100%? (98-99.5%)
The recommended regimen for rhTSH administration is 2 intramuscular injections into the buttock given 24 hours apart. What dosage is used for each injection?
What is 0.9mg?
How was ablation success measured in the ESTIMABL study?
What is neck US and stimulated Tg of < or equal to 1.0 ng/mL?
What are 3 benefits to buying directly from Sanofi?
What is
A routine diagnostic WBS is recommended either with rhTSH or THW, how long after ablation in intermediate and high risk patients? Low dose RAI should be used.
What is 6-12 months?
What is the half life of rhTSH?
What is 25 hours plus or minus 10?
What adverse reaction occurred in 11% of patients according to the clinical studies?
What is nausea?
If an office is purchasing Thyrogen through a distributor or wholesaler can they still use the online portal to submit a prescription form?
What is Yes, they can?
Before considering any additional therapy, post op disease status should be considered.
Post op status maybe assessed with either stimulated or unstimulated Tg testing. This guidance comes from what recommendation?
What is Recommendation 50? (A & B)
If rhTSH is administered with radioiodine, then the contraindications for radioiodine also apply to this combination regimen. What section of the PI is this?
What is Contraindications?
How many of the 8 QOL domains in the SF-36 scale showed statistically significant negative changes following THW in the diagnostic study Haugen et al?
What is 8 out of 8?
If an office is buying direct from Sanofi and they are having issues with an order placed, who would they contact for assistance besides us?
What is Sanofi Trade Operations/rhTSH Operations?
Dr. Stein has a high risk patient he needs to ablate. Since you are the Thyrogen rep, he asks you if Thyrogen is a viable preparation option for this particular patient. What would Recommendation you tell him?
What is Recommendation 54? (C7D)
What does the SF-36 scale measure?
What is Physical and Mental functioning of a patients health status?
THT alone missed what percent of metastatic disease compared with rhTSH stimulation
What is 21%?
Both financial assistance programs offered through Sanofi for Thyrogen will not apply for patients on what type(s) of programs?
What is Federal?
1.Dr. Rao has a patient whom she has been following up for a couple of years because the patient has had an incomplete response to RAI ablation before. You’ve uncovered by probing Dr. Rao that the patient has no anti Tg antibodies. She now wishes to do a Stim Tg test but is uncertain how to prepare the patient – Thyrogen or THW? What recommendation would you go to and what would you tell her?
What is Recommendation 63? (C)
What mean peak serum TSH concentration value is reached after one injection?
What is 116mU/L?
In the clinical studies for rhTSH, as an adjunctive diagnostic tool, the overall rates of positive concordance in Ladensen and Haugen, were what respective percentages?
What are 79% and 82%?
What is the purpose of the prescription support form?
What is get T1 started in the process of reviewing patient’s insurance for benefit verification?