Topic 8: Control of Gene Expression I
Ability to alter gene expression patters in response to extracellular cues, and reestablishing baseline upon their removal
What is Dynamic Adaptability
This type of feedback loop leads to cell memory and transcription of it's own gene
What is a positive feedback loop
This type of hydrophobic tail is known for it's "kink" due to a double bond.
What is an unsaturated tail?
In this conformation, the binding site of transporter proteins is not accessible from either side of the membrane.
What is the occluded conformation
Gated Transport, transmembrane transport, vesicular transport
What is protein movement
Sorting signals to the nucleus responsible for the selectivity of active nuclear import process
Helix-turn-Helix, Leucine Zipper, Helix-Loop-Helix, Zinc Finger proteins
What are Cis-Regulatory Sequence binding motifs
This gene in Drosophila has a positional information regulation with two activators and two repressors that affect the regulation of striping patterns.
What is Eve?
Where are lipid droplets processed in the cell?
What is Endoplasmic Reticulum.
The sodium-potassium pump maintains intracellular Na+/K+ concentrations, and is an example of which type of ATPase?
What is a P-type ATPase
Site of storage of intracellular Ca2+, production of transmembrane proteins and lipids, start site of most secreted proteins
What is ER Function
What is importins
A part of the DNA where the general transcription factors and the polymerase assemble
What is promoter region
Term for which a DNA methylation results in expression of a gene from only one parent.
What is genomic imprinting?
What is the barrier called that separates both protein and lipid molecules?
What is Tight Junction.
Automatic inactivation of which ion channel saves a cell from repeatedly self-amplifying an action potential?
What are Na+ channels
Large hydrophobic pocket lined by methionine with unbranched flexible side chains
What is Signal sequence binding site
This regulatory protein triggers the hydrolysis and conversion of RAN-GTP to RAN-GDP
What is GTPase activating protein ( GAP)
In the absence of glucose, the bacterium makes cAMP which activates THIS protein switch on genes that allow the cell to utilize lactose
What is CAP ( catabolite activator protein)
This creates new isoforms from the same gene.
What is alternative splicing.
What is the term used to describe the carbohydrate-rich zone on the cell surface?
What is Cell Coat or Glycocalyx.
Opening of K+ gated channels and inactivation of Na+ channels repolarizes the membrane during this phase of an action potential.
What is the falling phase
Proteins containing a retention signal of 4 amino acids at the C-terminus (KDEL)
What are ER resident proteins
What is ATP hydrolysis
These DNA sequences divide the genome into independently regulated domains, preventing distant cis-regulatory sequences from regulating the wrong gene.
What are insulator sequences
This type of nucleic acid keeps transposons in "check" making sure they do not enter the germ line during gametogensis.
What are Piwi-interacting RNAs
What is a principal component that helps maintain the structural integrity and shape of the plasma membrane in red blood cells?
What is Spectrin.
The binding of ions to this functional group within the selectivity filter determines the degree of specificity of an ion channel.
What is a carbonyl group
Serve as trimers measuring how long a protein has spent in the ER, help distinct misfolded and newly formed proteins.
What are N-linked Oligosaccharides
Nuclear reassembly later in mitosis is dependent on this positional marker for chromatic nuclear localization
What is RAN-GTP bound to chromatin