Historical background/introduction
What is protein sythesis?
What is the process of making protein in cells?
What is active site mutation?
What is a mutation that changes the shape of an enzyme?
What range was Lucy's white blood cell count (Low, Normal, High)?
What is a low blood white cell count?
What is our evidence for Lucy's stop codon mutation?
What is an amino acid deficiency and a premature stop codon in the ADA mRNA Transcript?
What mutation does Lucy have?
What is a stop codon mutation?
What is transcription? Where does it happen?
What is the process of DNA being written into mRNA? What is the nucleus?
What is a stop codon mutation?
What is a stop codon occurring too early in an amino acid sequence?
What are the possibilities of Lucy's diagnosis?
What are HIV and ADA - SCID
What does the stop codon mutation do for Lucy's ADA - SCID?
What is making her protein misshpapen so it cannot break down deoxyadenosine?
What will happen to Lucy's white blood cell count?
What is an increase in her white blood cell count?
What is translation? Where does it take place?
What is translating mRNA to amino acids? What is Ribosome?
What is a tRNA error?
What is an mRNA that codes for the wrong amino acids?
What are Lucy's levels of HIV proteins and Deoxyadenosine nanomoles/liter?
What are not present HIV proteins? What are high Deoxyadenosine nanomoles/liter?
FREE POINT: Who is your favorite group member?
What will stem cell therapy do to Lucy's deoxyadenosine count?
What is a decrease in Lucy's deoxyadenosine count?
What conditions interrupt protein synthesis in the gizmo?
What are active site mutations, stop codon mutations, and tRNA errors?
What are the types of mutations?
What are deletion, insertion, & substitution?
What happens when a patient has HIV?
What is high HIV proteins in a patient's blood sample?
What is our evidence against HIV?
What is no present HIV proteins?
What is bone marrow being removed and altered to create the correct stem cells which then change into white blood cells?
What is stem cell therapy?
What is the process of protein synthesis?
What is Translation from DNA - mRNA, Transcription mRNA - tRNA - Amino acids?
What is Lucy suffering from? What does it do?
What is ADA - SCID? What is a stop codon mutation that caused the enzyme which breaks down deoxyadenosine to be misshapen?
What happens when a person has ADA - SCID?
What is a high concentration deoxyadenosine in the blood?
What is our evidence for Lucy's ADA - SCID?
What is a high deoxyadenosine count?
What will stem cell therapy do to help Lucy?
What is the altered stem cells increasing her white blood cell count, enabling her to be able to break down the toxin doexyadenosine?