The Standard of Care, Blood Culture
The majority of blood culture contamination is caused by this pathogen.
What is S. epidermidis?
This drug combination is the most common form of empiric therapy for gram negatives.
What is Piperacillin/Tazobactam (Zosyn)?
T2MR provides pathogen ID in this many hours.
What are 3-5 hours?
These are the three values that are used to calculate NPV and when you increase THIS one, NPV decreases.
What are the sensitivity, specificity and incidence rate and as incidence rate increases, NPV decreases?
According to Pfeiffer and Clancy, Blood culture is missing this percentage.
What is 40-50%.
This pathogen is found more often in polymicrobial infections than any other pathogen.
What is E. faecium?
The Candida mortality rate if appropriate therapy is administered within twelve hours of the presentation of symptoms.
What is 11%?
This Danish bacteriologist first introduced one of the most crucial staining techniques in microbiology in 1882.
Who is Hans Christian Gram? (Gram stain)
According to Klaerner, pre-incubated P. aueriginosa went undetected by blood culture in in this percentage of isolates.
What is 46.9%
The IDSA guidelines state this about S. aureus bacteremia.
What is "CVCs should be removed immediately when they are found to be the source of S. aureus bacteremia?"
According to the DIRECT2 paper, T2Candida detected this many additional patients that were missed by the companion blood culture.
What is 37?
In conjunction with empiric therapy, T2Bacteria and T2Candida empower clinicians to effectively treat this percentage of patients.
What are 95% of patients within hours of presentation?
According to the She study, up to this % of physicians would narrow therapy based on this result alone.
What is 85?
The mortality rate of ineffective empiric therapy exceeds 30% with this deadly pathogen that is included on our panel.
What is pseudomonas aeruginosa?
These members of the T2Bacteria Panel are the top two most common pathogen Isolates from the ED.
What are E. coli and S. aureus?
These are two common resistance mechanisms associated with K. pneumoniae infections.
What are ESBL and KPCs?
This percentage of patients receive antimicrobials prior to blood culture draw.
What are 50-70% of patients?
A patient with E. faecium infection is at risk for this kind of resistance and the targeted therapy would include these drugs. (Two answers required)
What is VRE and Linelzolid/Daptomycin?
The T2Bacteria Panel includes these pathogens.
E. coli, P. aeruginosa, E. faecium, S. aureus, K. pneumoniae
These four drugs are used for de-escalation and escalation from vancomycin Rx.
What are de-escalation drugs nafcillin and oxacillin and escalation drugs linezolid and daptomycin?