Tyrannosaurus-Bex
The branded name for Bexarotene
What is Targretin
The generic name for Adcetris is what
What is brentuximab vedotin
An reformulated topical agent based on Nitrogen Mustard
What is Valchlor
romidepsin belongs to this class of drugs
What are HDAC inhibitors
Bexarotene is in a class known as what?
What are retinoids
Gabapentin or Neutontin are often prescribed due to what common adverse event?
What is peripheral neuropathy
Psoralen is taken when this skin directed therapy is initiated
UVA or PUVA
Indicated in the treatment of ______ in patients who have received at least one prior systemic therapy
What is CTCL
Two ways of administration for Bexarotene
What are topical and oral
The ALCANZA trial evaluated patients with MF or what?
What is pcALCL
This skin directed therapy is considered not as effective for tumor stage MF
What is PUVA
Days 1, 8 and 15 represent a cycle length of _____ days
28
A patient on Bexarotene recently started atorvastatin and L-thyroxine, indicating what?
67% and 20.3% represent what from the ALCANZA trial?
ORR
Commonly used as a first line CTCL treatment with blood involvement and erythrodermic stages
What is ECP
Based upon 2 clinical trials, the ORR were ____ and ______
33% and 25% (CR+PR)
PR and CR with oral Bexarotene 300mg/m2/day in tumors
1.6% and 30%
Percentage of patients who had a CR
What is 15.6%
Considered to be the single most effective therapy for MF
What is TSEBT
Patients with advanced stage disease and/or high tumor burden at risk for what AE?
Tumor lysis sydrome