Football
Which coach has won the most Super Bowl championships?
Bill Belichick
Which champion was once the protector of Shurima?
Azir
What is the largest muscle in the human body?
Gluteus Maximus
What drug was commonly used to enhance the recipe of the famous drink Coca-Cola?
Cocaine
What Will Wright created video game series released in 2000 saw players watching and directing characters to mundane things like eating, sleeping, and cleaning their houses?
The Sims
Which NFL team had the most wins in the 2000s?
The Indianapolis Colts
What were the only skin lines with music videos?
K/DA and True Damage
The human retina contains receptor cells of two different types: rods and what?
This drug is commonly known for its gruesome effects of deteriorating the body from the inside out, and patches of scaly skin.
Crocodil
What video game came with the Nintendo Entertainment System when it was released in the late 1980s, and was meant to be played with the NES Zapper gun?
Duck Hunt
Where is the NFL Hall of Fame located?
Canton, Ohio
What is the Ultimate ability of Zed called? (Bonus for damage done on end)
Death Mark
What is the purpose of Red Blood Cells and White Blood Cells?
Red Blood Cells - Carrying oxygen throughout the body
White Blood Cells - Fighting off foreign bodies inside your body.
What sometimes forgotten, but legal, drug is associated with nausea, loss of balance, slurred speech, and possible loss of conciousness?
Alcohol
What do the main 3 shells do in Mario Kart when thrown?
Green - Free Throw
Red - Tracking
Blue - Tracking first place
What two sports did American Football generate from?
Soccer and Rugby
Who is Gragas' drinking buddy?
Jax
The four major lobes of the human brain are the frontal lobe, the parietal lobe, the occipital lobe, and what?
Temporal Lobe
What drug, sharing the name with a relaxing agent, was associated with "zombie-like" symptoms such as increased pain tolerance, loss of reasoning, and hyper aggression?
Bath Salts
Released in March 2020 for the Nintendo Switch, what title in the Animal Crossing franchise immediately became immensely popular as a way to keep in touch during COVID-19-related lockdowns?
New Horizons
How many teams did the NFL have when it first started?
10 Teams
There were 3 minor passives exclusive to certain characters and interactions that have since been removed. Name me one of them. Bonus for the other two
Enemies that had Sunglasses in their splash/model took 1 less damage from light based spells (Leona/Lux)
Ninjas work best alone. Ninjas did 1 less damage for every other ninja on your team (Zed/Akali/Shen/Kennen)
Maokai and Zyra would grow slightly when hit by a Leona spell (Plants + Sunlight)
What single-word term refers to the body’s ability to regulate various physiological processes to keep internal states steady and balanced?
Homeostasis
Name me the 6 main types of drug categories (Bonus for 7th)
What are the 3 ways to receive a 1-Up in Mario? (Bonus for little known 4th niche)
Collecting from a block, Grabbing 100 coins, and Killing 10 enemies in a single jump without touching the ground. (Top of the flag pole)