Mitochondria as a Pacemaker
Reactive oxygen species (ROS) can damage basic building blocks of the cell. Hydrogen Peroxide loses this to become harmless
What is Oxygen?
The amount of energy that Glycolysis produces
What is 4 ATP?
The animal human neurons are xenotransplanted into
What are mice?
True or false: the circadian rhythm function without light
Tis true?
Hyperoxygenation is a process by which the amount of oxygen is increased. This enzyme scavenges for Hydrogen peroxide
What is Peroxiredoxin?
The more efficient way to produce ATP
What is OXPHOS?
The method to achieve synchronisation between transplanted neurons and the host brain
What is manipulating mitochondrial function?
The country VIB located in
What is Belgium?
Mitochondria are the powerhouse of the cell. This has the highest level of product in the morning
What is ATP?
Controls key enzymes like the ones in the TCA cycle and OXPHOS
What is Ca2+?
The potential cause for neurodevelopmental disorders
What is mitochondrial dysfunction in neurons?
The ancestors of animals and plants
What is archaea and cyanobacteria?
PRX III goes through two loops, and this cycle involves the inactivated version of the enzyme
What is Sulfenylation cycle?
What can happen to cells when Ca2+ increases to a certain level
What is neuronal degeneration/cell death?
Define neoteny
What is an extended period of development?
The animal used to test the ARHGAP11B gene
What are marmosets?
Fill in the blank: Mammals have an established negative autoregulatory __________ - ___________ feedback loop
What is Transcriptional-Translational?
ROS will cause this speed of progression to neuronal fate (increased/decreased)
What is increased?
The type of stem cells that will be used for modelling diseases.
What are pluripotent stem cells?
The three lead researchers (spelling matters).
Who are Pierre Casimir, Ryohei Iwata, Pierre Vanderhaeghen?