Organs
Name 3 regenerative organs
1.Kidneys
2.Liver
3.Pancreas
How long does the stem cell process take
A few weeks - A few months
How many stages are involved in this process
3
What is the purpose of scaffolding
To cause cellular interactions using stem cells that can contribute to organ/tissue regeneration
What does ECM stand for
Extracellular Matrix
what's the max amount an organ regenerate by itself
1cm
Why are stem cells ideal for being programmed to have different functions?
Stem cells are regenerative and are able to duplicate themselves. They also can easily become a cell with other functions.
What is the purpose of regenerative medicine
A way of restoring, replacing, or fixing organs/tissue that is infected, damaged, etc, all without "surgery" or drugs
What is the scaffold material made out of?
A synthetic dissolving polymer (polylatic acid) but on the rare occasion can be made up of other biomaterials.
What is the importance of the ECM
It provides structural support for cell migration and tissue rebuilding during the healing process of tissues. It also controls cell behaviour and can regulate cell growth. It is key for successful recovery
What has to happen before the scaffolding process begins in the regenerative process of an organ
Cells from the infected organ need to be extracted and expanded. If that effected area can not be accessed for some reason, cells will be taken from another area.
What is the difference between stem cells and regular cells
Stem cells have the ability to renew and divide themselves over a period of time. They also do not have one specific function and can perform a number of different tasks. Stem are however able to become a specialized cell.
Name and describe the 3 stages of human regeneration
Molecular: Creates diversity, signs pathways, triggers cell division, part of the chemical process
Cellular: Involved in the renewal of cells and provides the body with healthier cells, creates new cells to fulfil the spot of missing ones
Tissue:The body responds to injury, repairs and restores damaged areas, fights against infections, new cell generation, and heals trauma
Describe the scaffolding process
1. Biopsy from patient
2.Cells are taken for cell isolation
3. Cells are civilized and proliferated
4. Cells are then put onto scaffolding material
5.Tissue development happens
6. Implantation
How has bioprinting helped regenerative medicine?
Enables precise placement of cells, helps with growth factors to create complex tissues, constructed based on patients needs. Bioprinting is also the future to overcoming organ shortage.