DEFINITIONS
NATURAL CHIMERISM
ARTIFICIAL CHIMERISM
TESTS FOR CHIMERISM
POTPOURRI
100

Someone with cells from more than one zygote in them.

human chimera

100

What do we call a mother who got cells from her fetus during pregnancy?

Fetal chimera

100

How are man-made chimeras created?

transplantation tissues or organs

100

This test uses specific enzymes to cut out specific genes, multiply those genes segments, and then run the gene segments through gel electrophoresis.

PCR (polymerase chain reaction)

100

Which of these is a lie?

Mrs. Winkler used to be a cabinet builder.

Mrs. Winkler has herded sheep on horseback.

Mrs. Winkler enjoys botany and is great with plants.

enjoys botany, good with plants

200

Someone who has non-human cells transplanted in them.

xenotransplant chimera

200

What do we call a baby who got maternal cells in when they were in utero?

Maternal chimera

200

What is one difficulty or increased risk that man-made chimeras face?

Risk of rejection or out-competition of transplanted cell line.

200

This procedure takes chromosomes from a cell and pairs them up to look at.  This can be used to identify chromosomal differences between cells when looking for chimerism.

karyotyping

200

What fish breeds by obligate chimerism.

anglerfish

300

Someone with a very small amount of cells from someone else (<1%)

microchimera

300

What do we call it when one baby is born with the cells of their ghost twin or vanished twin in them?

fusion chimerism

300

Name a real life example of a way doctors create a xenotransplant.

Using gene-edited pigs to make heart valves for humans.

300

This test checks for proteins on the surface of red blood cells and can be used identify if blood cells are being made in bone marrow from different zygotes (with different genes).

Blood typing

300

What is Mrs. Winkler's younger sister's name who Mrs. Winkler believes is a fusion chimera?

Iris

400

Someone who is a chimera without having had a medical procedure that made it happen.

natural chimera

400

What do we call it when twins are born that exchanged cells in utero and contain cells from each other?

Twin chimerism

400

What procedure for infertility increases the chance of twin chimerism?

In vitro fertilization

400

This genetic test uses specially glowing nucleotide probes that combine with specific gene sequences in chromosomes of a cell, allowing for the identification of  an individual donor cell in a background of recipient tissue.

Fluorescence in situ hybridization (FISH)

400

What band sings the Mr. Roboto song?

Styx

500

A test used to detect numerical and structural chromosomal abnormalities.

Karyotype

500

What are two physical traits that can be used to identify natural chimeras without doing genetic testing?

Different colored eyes and different skin tones on one person

500

What is the name of Han Solo's wookie friend/sidekick in Star Wars?

Chewbacca

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