Management plus Treatment
Methods such as a Mediterranean diet and functional exercise can help reduce this to better treat F5L
What is weight management?
This drug initially used as Rat poison is considered a treatment option for F5L
What is Warfarin or Coumadin?
This test is used to confirm for Factor 5 Leiden that tests for functional coagulation time such as activated partial thromboplastin time
What is an activated protein C resistance test
Leg pain and swelling are possibly indicative of this condition for Patients with FVL
What is DVT?
Factor V Leiden is was discovered in this city in the Netherlands
What is Leiden?
This this condition that looks like a polo mint in a MRI with contrast can be avoided by
What is physical activity and avoidance of sedentary lifestyle
Warfarin requires a regular checkup of this lab value every 1-4 weeks
What is PT INR?
A value of 0.5 or above indicates what in a D Dimer test
A blood clot
This risk factor is found in this demographic that also has a higher rate of Hereditary Spherocytosis and Cystic Fibrosis compared to the general population
What are Northern Europeans?
Caucasian is also acceptable
This substance that is found in smooth ER with tubular mitochondria is known to increase clotting proteins in the body
What is estrogen?
Individuals with this genotype in Factor V Leiden undergoing surgery should receive anticoagulant prophylactics
What is homozygous?
Dabigatran was more frequently reported than rivaroxaban to have this condition
What is dyspepsia?
One can find a this type of mutation in this gene from a genetic test
point mutation of Arginine to Glutamine in the F5 gene
Sudden shortness of breath, chest pain , and coughing up blood are signs of this condition in those with F5L
What is pulmonary embolism?
This activity that acts on the pre and post ganglionic sympathetic receptors is a potential risk factor for Factor V Leiden
What is smoking?
Pregnancy increases the risk of VTE by this much with FVL affected individuals
What is 4-5 times?
Rivaroxaban requires monitoring of eGFR and BUN which indicative test of this organ
What is this kidney?
This characteristic of a vein in an ultrasound is how to primarily diagnose for DVT
The veins of muscles are affected during a DVT
What are the calf, gastrocnemius, and soleus muscles
Protein C is known generally as the "brakes" in clot formation because of its ability to do this?
What is an anticoagulant?
Considered as a Class 1 medical device by the FDA due to being easily removable and not surgically implanted.
This device is advised for patients FVL in order to prevent DVT.
What are compression stockings?
How much cheaper is a 30 month supply of Warfarin compared to Dabigatran in cash without insurance?
What is100 times cheaper?
Warfarin costs 3 dollars per month vs Dabigatran is 300 dollars per month.
Acceptable values since drug prices are confusing i will accept are 60-120x cheaper
These conditions besides pregnancy could have a high D dimer test without blood clotting
Rheumatoid Arthritis, Heart Disease, Trauma, Recent Surgery, infection
If given a blood thinners during a D-Dimer test one can get a lower negative predictive value due to this inaccurate result
What is a false negative?
However, only about this % of individuals with the Factor V Leiden mutation ever develop abnormal blood clot
What is 10% ?