Pregananant
CANSA
Glucose Metabolism
Fats
100

Why do we only test for the beta subunit of hCG?

The Beta subunit is unique to hCG while the alpha unit is shared by FSH and LH

100

Dysfunction of this enzyme can increase cancer risk (involved in the cell cycle)

p53

100

Name the substrate and general features of GLUT1, GLUT2, GLUT4, and GLUT5

GLUT1: insulin-insensitive in brain

GLUT2: insulin-insensitive in liver and pancreas; high Kd

GLUT4: insulin-sensitive in muscle; low Kd but inhibited by glucose in cell

100

What transports fat from the intestines to adipose and liver tissue initially?

Chylomicrons

200

Name each important lipoprotein and where each one comes from

B-48: from intestines on chylomicrons

B-100: from liver on LDL, IDL, VLDL (Liver based)

C-II: on HDL and given to VLDL; activates LPL

A-1: on HDL activates LCAT

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