Antibiotics
Tetracyclines
GI discomfort-GI ulcer, Esophog Ulcer
Don't take laying down or at bedtime
Hepatotoxic
Don't take on empty stomach
Photosensitivity
Tooth discoloration
Don't take w? milk, calcium, iron, magnesium
Contradictions in 8 years old and younger, pregnant women
Sulfamethoxazole/ Trimethoprim
Used for UTI'S
stops growth preventing synthesis folic acid
ADVERE- SJS, blood dyscrasias, crystalluria, hyperkalemia
Contradicted in pregnancy/lactation
Monitor K+, PLT, WBC, RBC
ED- hyperkalemia, hormonal contraceptive, take on empty stomach or w? water, I&O
s/s- rash, anaphylaxis
manifestations- decrease of UTI, negative urine culture, normal WBC
Acyclovir
Prevents reproduction of viral DNA
Treats Herps simplex/ varciella zoster type viruses
Nephrotoxic
NOT A CURE
Mild GI discomfort
Drink H2O on this med
Rifampin
Combative w? Isoniazid
Active TB patients
Hepatoxic
2nd form of contraceptive
Take on empty stomach
Side effect- red/orange color secretion
Chemically similar to penicillin
Cross sensitivity
anaphylactic to penicillin
Nephrotoxic
AVOID ALCOHOL (concurrent to Disulfiram reaction)
S/S- Call 911, Epi Pen
Fluoroquinolones (Ciprofloxacin)
Wide variety of infections
Bacteriacidal
GI Discomfort
ADVERSE- Achilles tendon rupture, suprainfection, phototoxicity
Contradictions- pt younger than 18yrs old
Monitor WBC and kidney labs
ED- report pain, swelling, redness @ achilles tendon, yeast, c.diff, avoid the sun
take w? meal
Isoniazid
Latent TB
Hepatoxic
Causes Neuropathy (burning, numbness, tingling)
2nd form of contraceptive
Gentimicin
Nephrotoxic
Ototoxic
Neuromuscular depression (resp desp, muscle weakness, myasthenia gravis)
Contradicted for patients with kidney impairment and hearing loss
s/s- non hormonal contraceptive
Ketoconazole/ Fluconazole (AZOLE)
Nephrotoxic
Electrolyte Imbalance
Bone marrow suppression (not producing enough blood cells, RBC, WBC, PLT, Thrombo)
Monitor K+ levels, CBC, Hemocrit
Nitrofurantoin
UTI'S & prophylaxis for recurrent lower UTI'S
GI discomfort
Rust yellow/brown urine
Stain teethe
ADVERSE- Hypersensitivity, blood dyscariasis, periphal neuropathy, headaches, dizziness
Contradictions- Older pt's w/ renal impairment
Monitor PLT, WBC, RBC
Take w/ meal
Erythromycin
Hepatotoxic
GI discomfort, prolonged QT levels, cardiac death, dysrhythmia, nausea, vomiting
Ototoxic, test for hearing loss
Contradictions are Liver disease, QT prolongation, monitor for liver function
SERIOUS CASES- Vertigo, tinnitus, hearing loss
Nystatin (Polyene)
Nephrotoxic
Hyperkolemia
Phenazopyridine/Analgesic
Relieve UTI symptom ONLY
AZO dye function as local anesthetic on mucosa of urinary tract
Side effect- pee turns orange/red
stains clothes
GI discomfort
take w/ meal
Vancomycin
Indicated for MRSA, C.DIFF, YEAST, STEPHO
BIG EARS BIG KIDNEYS, Nephrotoxic and Ototoxic
Redman Syndrome- slow infuse (60 minutes)
S/S- itching, rash, flush, tachycardia, hypotension
renal and abdominal toxicity
MONITOR TROUGH LEVELS