Antacids
Action
–Neutralizes / buffers HCl
•Decreases gastric acidity
Adverse Effects
magnesiu
aluminum
calcium
sodium bicarbonate
Indications
nHyperacidity
–Heartburn
–Acid indigestion
–Acid reflux
–Gastro Esophageal Reflux Disease (GERD)
Peptic Ulcer Disease (PUD
Nursing Implications
–Relationship to other drugs (Contradictions)
History (Medications, Health)
Bowel sounds, Stool changes
Electrolyte monitoring
Antacids causes what Electrolyte imbalances
–Hyperphosphatemia
–Calcium replacement
–Magnesium deficiency
H2 Blockers / Antisecretory
–Decreases volume and acidic environment of the stomach
•day and night
Goals of Antacid Therapy
–Reduce pain
–Usually the Normal Ph is 3 to 4
–The Goal is to reduce the acid environment
H2 blocker Drugs
–cimetidine (Tagamet)
–famotidine (Pepcid)
–ranitidine (Zantac)
–nizatidine
Name the types of Antacid Drugs
–magnesium hydroxide (Milk of Magnesia)
–aluminum carbonate (Basaljel)
–aluminum phosphate (Phosphagel)
–aluminum hydroxide (Amphojel)
–calcium carbonate (Tums)
sodium bicarbonate (Alka Seltzer
H2 Blockers / Antisecretory Adverse Effects. Name 4 categories of adverse effects
CNS: Dizziness, drowsiness, headache, disorientation, hallucination, depression
Cardiac: ¯ HR, ¯ BP, cardiac arrhythmia
MS - skin rash, muscle pain
Hematological - ¯ bone marrow (RBC, WBC, platelets)
GI - Diarrhea
Men - ¯ sperm count, impotence, gynecomastia