Basics of SickleCell
What is sickle cell disease?
What is a genetic blood disorder that affects red blood cells?
Is sickle cell disease inherited or contagious?
What is inherited
What is the term for episodes of intense pain?
What are pain crises (or sickle cell crises)
What is the only known cure for sickle cell disease?
What is a bone marrow or stem cell transplant
What month is National Sickle Cell Awareness Month in the U.S.?
What is September
Which shape do red blood cells take in sickle cell disease?
What is a crescent or sickle shape
What kind of trait must be inherited from both parents to have the disease?
What is a recessive trait
What organ is commonly damaged in early life in sickle cell patients?
What is the spleen
What medication is commonly prescribed to reduce pain crises?
What is hydroxyurea
Which racial/ethnic group is most commonly affected by sickle cell disease in the U.S.?
Who are African Americans
Which protein in red blood cells is abnormal in sickle cell disease?
What is hemoglobin
What genotype represents someone with sickle cell disease?
What is SS
What is the condition of having low red blood cell count called?
What is anemia
What vitamin is given to help prevent infections?
What is folic acid (or penicillin in early childhood)
In what year was sickle cell disease first described in medical literature?
What is 1910
What is the full name of the most common form of the disease?
What is sickle cell anemia
What does the genotype AS indicate?
What is sickle cell trait (carrier)
What type of stroke can sickle cell patients be at risk for?
What is an ischemic stroke
What kind of transfusion may help manage severe symptoms?
What is a blood transfusion
What organization in the U.S. funds research and supports sickle cell patients?
What is the Sickle Cell Disease Association of America (SCDAA)
What major issue does the sickle shape of cells cause in the bloodstream?
What is blockage of blood flow due to clumping or sticking of the cells
What are the chances a child will have sickle cell disease if both parents are carriers?
What is 25%?
What dangerous lung complication can occur in sickle cell patients?
What is acute chest syndrome
What new gene-based therapy was approved to treat sickle cell disease (as of 2023)?
What is CRISPR-based gene therapy (or gene editing therapy)
Why is sickle cell trait more common in areas with malaria?
What is because it provides some protection against malaria