Case 1
Case 2
Case 3
100

After breakfast, Glo Cose entered the Glyco Gate Kiosk. She found a Cornetto voucher, which rewards her 2 ATP coins as her starter scoop. At the Lactato Mini Cone (RBCs), the deal was tiny, just 2 scoops and a plain cone. Enough to survive, but nothing fancy. At the Malata Supreme Cone (Liver), the deal was grand: a full 32-scoop ice cream cone, loaded with Glyco Sprinkles and Fat Fudge Toppings for take-out. At the Fadhuz Speed Cone (Muscles), the service was quick, 30 scoops, good for fast energy but not the max. 

As Glo enjoyed her cones, a friend tapped her shoulder and asked: “Uy Glo! Dami niyan ah. Hanggang saan aabot Glucose mo?”


After claiming the cornetto voucher from the Lactato Mini Cone, what is the net ATP yield, and how is it produced?

A. Net 2 ATP, produced through oxidative phosphorylation

B. Net 4 ATP, produced through substrate-level phosphorylation

C. Net 2 ATP, produced through substrate-level phosphorylation

D. Net 32 ATP, produced from both glycolysis and oxidative phosphorylation

C. Net 2 ATP, produced through substrate-level phosphorylation

100

In-CELINE deposits her gluCOINS in the bank (liver) for safekeeping when she has too much of it


What is the storage form of gluCOINS when In-CELINE deposits it to the bank?

A. glucose

B. glucagon

C. glycogen

D. glycogenin

C. glycogen

100

Once upon a time, trouble was brewing inside Hiker Joey’s body. He had been stuck in a snowy cabin for 3 days with no food. Initially, Glyco-genie gave him sugar to keep his brain and muscles running, but when he woke up the second day, Glyco-genie was gone!

That’s when O-LIVER, the de-LIVER-y man arrived and shouted, “No carbs? No problem!” He called his companions Gly Hero-I, Sir Alan the Amigo Acid , and Lenny Lactate. 

They used their magic to make a new genie, named Gluco-genie, who can rescue Joey and give him great sugar to feed his brain! Even without eating, Joey can stay alert with the help of Gluco-genie.


What is the name of the process where Gluco-genie took place with the help of Gly Hero-l, Sir Alan the Amigo Acid, and Lenny Lactate?

A. glycolysis

B. gluconeogenesis

C. glycogenolysis

D. glucogenesis

D. gluconeogenesis

200

After breakfast, Glo Cose entered the Glyco Gate Kiosk. She found a Cornetto voucher, which rewards her 2 ATP coins as her starter scoop. At the Lactato Mini Cone (RBCs), the deal was tiny, just 2 scoops and a plain cone. Enough to survive, but nothing fancy. At the Malata Supreme Cone (Liver), the deal was grand: a full 32-scoop ice cream cone, loaded with Glyco Sprinkles and Fat Fudge Toppings for take-out. At the Fadhuz Speed Cone (Muscles), the service was quick, 30 scoops, good for fast energy but not the max. 


As Glo enjoyed her cones, a friend tapped her shoulder and asked: “Uy Glo! Dami niyan ah. Hanggang saan aabot Glucose mo?”


During the Glay- Coli-Sees training, what equipment (enzyme) will slow down the work progress of the trainees? 

A. PFK1

B.Glucokinase 

C. L-Gulonolactone Oxidase

D. Ribulose 5 PO4 Isomerase

A. PFK1

200

In-CELINE deposits her gluCOINS in the bank (liver) for safekeeping when she has too much of it.


What regulatory enzyme should people call when they want to withdraw their gluCOINS from the bank?

A. glycogen synthase

B. glycogen phosphorylase

C. phosphoglucomutase

D. amylo-1,6-glucosidase

B. glycogen phosphorylase

200

Once upon a time, trouble was brewing inside Hiker Joey’s body. He had been stuck in a snowy cabin for 3 days with no food. Initially, Glyco-genie gave him sugar to keep his brain and muscles running, but when he woke up the second day, Glyco-genie was gone!

That’s when O-LIVER, the de-LIVER-y man arrived and shouted, “No carbs? No problem!” He called his companions Gly Hero-I, Sir Alan the Amigo Acid , and Lenny Lactate. 

They used their magic to make a new genie, named Gluco-genie, who can rescue Joey and give him great sugar to feed his brain! Even without eating, Joey can stay alert with the help of Gluco-genie.


Which cycle is Lenny Lactate a part of to convert it to Gluco-genie?

A. lactate cycle

B. alanine cycle

C. cori cycle

D. glucogenie cycle

C. Cori cycle

300

Lee Vur and, Musc Le are all applying in the Mito Cream Factory. Before employment, each of them undergo Glay-Coli-Sees Training where they are paid 2 coins after completion. However after training, Arbi Se was not accepted because they found out that he did not have an O2 Certification. Those that are employed are paid per cycle of their work. (1 NAD/hour = 2.5 coins, 1FAD/hour = 1.5 coins). 


What is one of the components needed in their training and working in the factory?

A. Retinol

B. Biotin

C. Thiamine

D. Ascorbic Acid

C. Thiamine

300

In-CELINE deposits her gluCOINS in the bank (liver) for safekeeping when she has too much of it.


What is the advantage of using glycogen-derived gluCOINS on an Energy Vending Machine (Glycolysis) compared to free gluCOINS?

A. Glycogen-derived gluCOINS enters as glucose-6-phosphate, saving 1 ATP.

B. Glycogen-derived gluCOINS enters as fructose-1,6-bisphosphate, skipping two ATP-consuming steps.

C. Glycogen-derived gluCOINS enters glycolysis as pyruvate, bypassing ATP use entirely.

D. Glycogen-derived gluCOINS requires an extra ATP to be phosphorylated.

A. Glycogen-derived gluCOINS enters as glucose-6-phosphate, saving 1 ATP

300

Once upon a time, trouble was brewing inside Hiker Joey’s body. He had been stuck in a snowy cabin for 3 days with no food. Initially, Glyco-genie gave him sugar to keep his brain and muscles running, but when he woke up the second day, Glyco-genie was gone!

That’s when O-LIVER, the de-LIVER-y man arrived and shouted, “No carbs? No problem!” He called his companions Gly Hero-I, Sir Alan the Amigo Acid , and Lenny Lactate. 

They used their magic to make a new genie, named Gluco-genie, who can rescue Joey and give him great sugar to feed his brain! Even without eating, Joey can stay alert with the help of Gluco-genie.

Describe how insulin and glucagon levels change in Joey’s body when he was stuck in the snowy cabin for 3 days? How does that affect Gluconeogenesis?

A. high insulin, low glucagon -> active gluconeogenesis

B. high insulin, low glucagon -> inactive gluconeogenesis

C. low insulin, high glucagon -> active gluconeogenesis

D. low insulin, high glucagon -> inactive gluconeogenesis

C. low insulin, high glucagon -> active gluconeogenesis

400

Arbi Se, Lee Vur and, Musc Le are all applying in the Mito Cream Factory. Before employment, each of them undergo Glay-Coli-Sees Training where they are paid 2 coins after completion. However after training, Arbi Se was not accepted because they found out that he did not have an O2 Certification. Those that are employed are paid per cycle of their work. (1 NAD/hour = 2.5 coins, 1FAD/hour = 1.5 coins).


Lee Vur earned 32 coins per work, what bus did he get on to go to work?

A. Cori cycle

B. Glycerol Phosphate Shuttle

C. Malate-Aspartate Shuttle

D. Carnitine Shuttle

D. malate-aspartate shuttle

400

In-CELINE deposits her gluCOINS in the bank (liver) for safekeeping when she has too much of it


In another branch located in MUSCLEton City, which employee can activate phosphorylase kinase so more gluCOINS can be released for withdrawal?

A. ATP

B. Glucose

C. Ca2+

D. Glucose-6-Phosphate

C. Ca2+

400

Once upon a time, trouble was brewing inside Hiker Joey’s body. He had been stuck in a snowy cabin for 3 days with no food. Initially, Glyco-genie gave him sugar to keep his brain and muscles running, but when he woke up the second day, Glyco-genie was gone!

That’s when O-LIVER, the de-LIVER-y man arrived and shouted, “No carbs? No problem!” He called his companions Gly Hero-I, Sir Alan the Amigo Acid , and Lenny Lactate. 

They used their magic to make a new genie, named Gluco-genie, who can rescue Joey and give him great sugar to feed his brain! Even without eating, Joey can stay alert with the help of Gluco-genie.


Which vitamin deficiency impairs pyruvate dehydrogenase and α-ketoglutarate dehydrogenase

A. Riboflavin

B. Thiamine

C. Niacin

D.Pantothenic Acid

B. Thiamine

500

Arbi Se, Lee Vur and, Musc Le are all applying in the Mito Cream Factory. Before employment, each of them undergo Glay-Coli-Sees Training where they are paid 2 coins after completion. However after training, Arbi Se was not accepted because they found out that he did not have an O2 Certification. Those that are employed are paid per cycle of their work. (1 NAD/hour = 2.5 coins, 1FAD/hour = 1.5 coins)


With Arbi Se not having an O2 certification, what type of Glay-Coli-Sees training did he undergo?A. Aerobic Glycolysis

B. Anaerobic Glycolysis

B. anaerobic glycolysis

500

In-CELINE deposits her gluCOINS in the bank (liver) for safekeeping when she has too much of it.


In-Celine uses glycogen synthase to deposit her gluCOINS to the bank. Why is glycogen synthase unavailable when In-Celine hasn’t earned gluCOINS for a while?

A. It is inhibited by glucose-6-phosphate

B. It is phosphorylated by phosphorylase kinase

C. It is dephosphorylated by protein phosphatase 1

D. It is competitively inhibited by glycogen phosphorylase

B. It is phosphorylated by phosphorylase kinase

500

Once upon a time, trouble was brewing inside Hiker Joey’s body. He had been stuck in a snowy cabin for 3 days with no food. Initially, Glyco-genie gave him sugar to keep his brain and muscles running, but when he woke up the second day, Glyco-genie was gone!

That’s when O-LIVER, the de-LIVER-y man arrived and shouted, “No carbs? No problem!” He called his companions Gly Hero-I, Sir Alan the Amigo Acid , and Lenny Lactate. 

They used their magic to make a new genie, named Gluco-genie, who can rescue Joey and give him great sugar to feed his brain! Even without eating, Joey can stay alert with the help of Gluco-genie.

As Joey's body shifts to gluconeogenesis to make the new Gluco-genie, glycolysis is turned off. Which allosteric change would happen to PFK-1 to shut down the reciprocal pathway of the product Gluco-genie?

A. A decrease in ATP and Citrate to inhibit it

B. A decrease in the enzyme's sensitivity to activators

C. An increase in AMP and Fructose 2,6-bisphosphate to activate it

D. An increase in ATP and Citrate to inhibit it

D. An increase in ATP and Citrate to inhibit it

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