Let's Lower Serum Lipids
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Pharmicokinetics
To Pee or Not to Pee...
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100

This lipid-lowering medication works by inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis.

What is atorvastatin

100

Your not a baby if you take this commonly prescribed drug in low doses to prevent a myocardial infarction or stroke.

What is aspirin?

100

Serum creatinine and GFR help the nurse assess this organ’s ability to clear drugs.

What is/are the kidney/kidneys?

100

This diuretic is used for rapid diuresis in heart failure and works at the ascending loop of Henle.

What is furosemide (Lasix)? 

100

The nurse knows that medications in this beta receptor antagonist drug class can block the signs and symptoms of hypoglycemia and ends in the suffix _______ .

What is -olol?

200

This medication lowers cholesterol by blocking absorption of dietary cholesterol at the brush border of the small intestine.

What is ezetemibe?

200

This anticoagulant requires monitoring of the aPTT to maintain therapeutic effect and reduce bleeding risk.

What is heparin?

200

Assessing AST and ALT helps determine this organ’s ability to metabolize medications.  

What is the liver?

200

This diuretic is an aldosterone antagonist often used in heart failure and cirrhosis.

What is spironolactone?

200

The nurse must teach the patient to sit or lie down before taking this self-administered, quick-acting sublingual antianginal drug to avoid dizziness from hypotension.

What is nitroglycerin?

300

This bile acid sequestrant lowers LDL cholesterol by binding bile acids in the gut so they are excreted in the stool.

What is cholestyramine?

300

This thrombolytic agent carries a high risk for bleeding and is contraindicated in recent surgery or hemorrhagic stroke.

What is alteplace?

300

This pharmacokinetic property is the time required for the plasma concentration of a drug to decrease by 50%.

What is half-life?

300

This diuretic works in the distal convoluted tubules to reduce sodium and water reabsorption and is often prescibed as a first-line treatment for hypertension. 

What is hydrochlorothiazide (HCTZ)?

300

This class of drugs lowers arterial blood pressure and controls angina by relaxing vascular smooth muscle and slowing cardiac conduction.

What are Calcium Channel Blockers

400

A nurse monitors liver function tests in patients taking this cholesterol-lowering drug.

What is atorvastatin?

400

This anticoagulant is preferred over warfarin due to its' increased efficacy and less bleeding risk for patients with atrial fibrillation who are at risk for a CVA.

What is apixiban (Eloquis)?

400

This process describes how oral drugs are extensively metabolized in the liver before reaching systemic circulation.

What is first-pass?

400

The nurse knows to monitor for the following 3 side effects when the patient is administered furosemide IVP. 

What are ototoxicity, hypokalemia, and hypotension?

400

This drug carries a black box warning for pulmonary toxicity, hepatotoxicity, and proarrhythmic effects.

What is amiodarone?

500

This drug is often combined with a statin for greater LDL-lowering effects.

What is ezetimibe?

500

Patients with recent cardiac stents often receive this medication along with aspirin for dual antiplatelet therapy.

What is clopidogrel (Plavix)? 

500

Drugs that compete for this plasma binding site can increase the free drug concentration and risk of toxicity.

What is protein-binding?

500

This diuretic can cause hyperkalemia and endocrine effects like gynecomastia.

What is spironolactone?

500

The nurse knows to assess the apical pulse prior to administration of this nondyhydropyrodine calcium channel blocker that is commonly used to treat atrial fibrillation, atrial flutter and Printzmetal's angina.

What is diltiazem?

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