Basic Facts
What does HPV stand for?
A. Human Protozoa Virus
B. Human Papillomavirus
C. Human Pathogenic Virus
D. Human Protein Virus
Human Papillomavirus
What kind of vaccine is Gardasil 9?
A. Recombinant, virus-like particle vaccine
B. Live attenuated vaccine
C. Inactivated virus vaccine
D. Toxoid vaccine
A. Recombinant, virus-like particle vaccine
What is “contraindication”?
A. A condition where the vaccine should not be used
B. A positive test result
C. A mild side effect
D. An injection site
A. A condition where the vaccine should not be used
In Vietnam, Gardasil 9 became available in:
A. 2014
B. 2016
C. 2020
D. 2022
D. 2022
> MSD introduced Gardasil 9 in Vietnam in 2022.
True or False: HPV only affects women.
False
How many HPV types are classified as high-risk?
A. 9
B. 16
C. 19
D. 31
C.19
What protein forms the VLP of HPV vaccine?
A. E6 protein
B. L1 protein
C. S protein
D. M protein
B. L1 protein
What is “immunogenicity”?
A. The ability to cause infection
B. The ability to provoke an immune response
C. The ability to destroy cells
D. The ability to replicate quickly
B. The ability to provoke an immune response
What is the price per Gardasil 9 dose at VNVC (Vietnam)?
A. 1,050,000 VND
B. 2,150,000 VND
C. 2,950,000 VND
D. 4,500,000 VND
C. 2,950,000 VND
You can catch HPV from hugging or sharing food.
False — HPV spreads mainly through sexual contact.
Globally, how many women die each year from cervical cancer?
A. 150,000
B. 250,000
C. 350,000
D. 660,000
C. 350,000
Each year, over 660,000 women are diagnosed and ~350,000 die from cervical cancer.
What is the immune mechanism of Gardasil 9?
A. It uses live weakened HPV
B. It uses virus-like particles (VLPs) without DNA
C. It directly kills HPV in the blood
D. It injects HPV DNA into the body
B. Virus-like particles (VLPs) without DNA
> VLPs mimic HPV’s shell, trigger antibody production, but cannot cause infection.
WHO’s elimination target for cervical cancer by 2030 includes:
A. 70% girls vaccinated, 90% screened
B. 90% girls vaccinated, 70% women screened, 90% treated
C. 80% girls vaccinated, 80% women screened, 80% treated
D. 100% girls vaccinated, 90% screened
B. 90% girls vaccinated, 70% screened, 90% treated
> The “90-70-90” target: 90% girls vaccinated, 70% screened, 90% treated.
You only need an HPV vaccine if you are sexually active.
False — The best time is before becoming sexually active.
Both Gardasil 4 and Gardasil 9 are produced by Merck & Co.
True
False
True
> Both are developed by Merck (MSD)
True or False : Gardasil 9 can cause HPV infection because it contains live virus.
False
> Gardasil 9 uses virus-like particles (VLPs) without DNA, so it cannot infect cells.
In Vietnam, the price per dose of Gardasil 9 is around ___ million VND.
3 million
HPV 16 and 18 cause about ___% of cervical cancers.
70
True or False: Common side effects of Gardasil 9 include mild pain at the injection site, fatigue, and low-grade fever.
True
> According to WHO & FDA, side effects are mild and self-limiting.
True or False : In Vietnam, there are about 4,000 new cases and 3,000 deaths from cervical cancer annually.
True