antifungals
what is amphoteracin used for
a severe systemic fungal infection
who can get a live attenuated vaccine?
children 2yo - 8yo intranasal
NEVER AN IMMUNOCOMPRIMISED PT
what does PCN G treat - and what are the sores of this disease called?
syphyllis - "chancre"
"the duration of time or the intensity of pain that a person will endure before taking overt action to relieve the pain, decreases with repeated exposure to pain, decreased by faitgue, anger, fear and sleep deprivation"
pain tolerance
what causes poorly localized radiating pain and how do we treat it?
visceral - internal organs and abdomen
opiates!
what is the therapeutic level of itraconazole
0.5-1mcg/ml
Mix and match
-oseltamivir
-zanamivir
-tamiflu/PO - give with food
-AE bronchospam and cough + avoid in CPOD/asthma
Oseltamivir - tamiflu/PO
Zanamivir - AE bronchospasm/cough - avoid COPD/asthma
how do you treat gonorrhea
ceftriaxone 1g IM and azithromycin (1 dose)
What is the classic triad of morphine toxicity
miosis, coma, resp depression
- treat: vent, narcan
which is more potent? morphine or fentanyl? and what considerations with a fentanyl patch?
fentanyl
- wear it for 72hr, takes 12hr to reach effects - give PRN breakthough pain meds until fentanyl patch takes effect
- heat accelerates the patch -dispose of carefully
Azole antigungal moa and main concer
inhibits ergosterol
Liver (monitor AST/ALT)
IVAPFK
what causes TTP - and what to do if it develops
valacyclovir - stop!!
how to treat in inpatient PID pt?
IV cefoxitin and cefotetan and also maybe doxy
what 6 things happen when a drug binds to a my receptor?
analgesia, resp depression, euphoria, sedation, decreased GI motility, physical dependence
yes - because it is mixed with tylenol
which one causes hallucinations, visual disturbances, color perception and is the DOC for aspergillosis
voriconazole
gangcyclovir is used for what?
CMV and herpes
when can symptoms of herpes simplex begin - and what antivirals do we use to treat it?
6-8hr after contanct, sores can heal and then remain latent until it recurrs again
Acyclovgir, famcyclovir, valacyclorvir
what drugs are agonist-antagonist opioids ? and what are some considerations?
pentazocine and butorphanol
- never give on an pure opioid dependent pt
durg for bone pain? neuropathic pain? and mucositis?
bone pain - nsaids
neuropathic pain - gabapentin
mucositis - magic mouthwash
which antifungal causes cardiosuppression
itraconazole
what is used for herpes simplex and varicella zoster - and what are its adverse effects?
acyclovir
PO - 5x daily
IV - phlebitis, nephrotox (infuse over 1 hr)
what treats pneumocystis jiroveci pneumoia?
bacteram
AE of clonidine (given for neuropathic pain)
severe HTN, rebound hypotension, bradycardia
What dose of hydromorphone (Dilaudid) is equivalent to 10mg of morphine?
1.5mg