Mechanism of Action
Sertraline belongs to this drug class.
What is an SSRI?
This sexual side effect is common with SSRIs.
What is decreased libido or sexual dysfunction?
Sertraline must NOT be taken with this class of antidepressant
What are MAOIs
The nurse should monitor for this serious mood-related risk in adolescents.
What is suicidal ideation?
Patients should avoid this substance due to worsening side effects
What is alcohol?
Sertraline primarily increases this neurotransmitter
What is serotonin?
This life-threatening reaction includes fever, tremors, and agitation
What is serotonin syndrome
Using NSAIDs increases this risk.
What is bleeding?
Best time of day to give sertraline if it causes insomnia
What is morning?
Explain why the patient shouldn’t stop sertraline abruptly.
What is risk of withdrawal symptoms?
What is increased serotonin do in the central nervous system
Better mood, personality and wakefulness
These are three side effects of SSRI’s
Weight gain, sexual dysfunction, suicidal ideation,
Two drug classes that may increase bleeding risk if combined with sertraline
What are anticoagulants and antiplatelets?
Nurses should evaluate this to determine therapeutic response
What is mood improvement/anxiety reduction?
Patients should report these new or worsening feelings immediately.
What is suicidal thoughts or drastic mood changes?
This syndrome can occur from excess serotonin
What is serotonin syndrome
These two drugs categories increase risk for bleeding when taken with sertraline
What NSAID's and anticoagulants
How long must a patient wait between MAOIs and sertraline?
What is 14 days?
Sudden discontinuation may lead to this.
What is withdrawal symptoms?
This is what inhibiting reuptake of serotonin do
What is increasing available serotonin in the synaptic cleft
This risk is crucial in children, adolescents, and young adults with major depression when on sertraline
Suicidal ideation
This is used to prevent withdrawal symptoms (dizziness, irritability, flu-like symptoms)
Do not stop abruptly
List three signs of serotonin syndrome.
What are fever, agitation, sweating, tremors, tachycardia, confusion? (Any 3)