Intracellular Compartments
Secreted and Membrane proteins are synthesized on a complex that is bound to the Endoplasmic Reticulum.
What is a Ribosome?
This is the major phospholipid making up the membrane of the ER.
What is phosphatidylcholine?
A translocator that randomly moves phospholipids between leaflets of membrane.
What is Scramblase?
The movement of a transport vesicle to the outside of the cell.
What is Exocytosis?
These proteins allow for the bending of the membrane during vesicle formation.
What are Clathrin and Bar Proteins?
Calcium is sequestered in this organelle and it can be released or re-sequestered in response to stimuli.
What is the Endoplasmic Reticulum (ER)?
The short stretch of amino acids, typically at the N-terminus that act as a cellular zip code.
What is the signal sequence?
The maintenance of lipid composition is maintained by a method that can be described as the moving or endoplasmic reticulum components to the plasma membrane.
What is vesicular trafficking?
This type of protein plays an important role in keeping vesicles full of neurotransmitters close to the cell membrane so they may be released quickly upon stimulation.
What are SNARE proteins?
Full complementation of miRNA with a target mRNA causes this to happen.
What is rapid degradation of the mRNA?
A concentration of molecules mediated by a protein or RNA scaffold that is not membrane bound.
What is a biomolecular condensate?
Translocation of proteins from the intermembrane space into the matrix space of the mitochondria is dependent on this translocator.
What is the TIM23 complex?
The name of 2 protein families that help ensure the vesicles bind/fuse to the correct organelles.
What are Rab and SNARE
This protein is activated by a GEF before inserting itself into the ER membrane where it recruits other proteins (like SEC23) needed to form COPII-coated vesicles.
What is Sar1?
A system which if mutated can lead to the improper budding of a properly formed vesicle, due to it not being able to free itself from the plasma membrane.
What is a Dynamin system?
The process that is thought to have given rise to intracellular organelles.
What are invagination and protrusions of the plasma membrane?
Proteins that are transported to the mitochondria post-translationally are kept unfolded by this protein.
What is hsp70?
In order for mitochondrial signal sequences to be transported to the mitochondria it must first be synthesized somewhere in the cytosol as a precursor protein.
What are ribosomes?
This molecule is embedded in the membrane, binds with AP2, and provides specificity for clathrin-mediated.
What is PIP (phosphoinositide)?
This organelle contains high concentrations of catalase and urate oxidase.
What are peroxisomes?
The presence of this terminus allows a Signal Recognition Particle, that circulates between the Endoplasmic Reticulum (ER) membrane and the cytosol, to bind, bringing the ribosome, mRNA, and growing peptide to the ER membrane.
What is a N-terminus?
A protein with a hydrophobic signal sequence that is already located in the mitochondrial matrix would be recognized by this protein in order to be inserted into the inner membrane.
What is the OXA complex?
Certain complexes assist in the N-terminal signal sequences guidance into the matrix space and folded into its proper conformation within the inner mitochondrial membrane.
What are TOM and TIM 23 complexes?
Resident ER protein in the golgi would find themselves being transported back to the ER in a vesicle coated by this.
What is COPI?
The type of transporter that transfers 2 different types of molecules across the plasma membrane in different directions.
What is an antiporter?