TRIPTANS AND APPETITE DRUGS
Migraine (with or without aura)
Schedule IV appetite suppressant that acts like norepinephrine
Phentermine
First drug ever approved for HIV
Zidovudine
Biguanide that causes GI upset and B12 deficiency
Metformin
The only insulin that can be given IV
Regular insulin
Black Box warning for Sumatriptan
Risk of MI / cardiac ischemia
Schedule II drug used for ADHD and Narcolepsy
Amphetamine
Antiviral prodrug activated by viral thymindine kinase
Acyclovir
GLP-1 agonist available as weekly SQ or daily oral
Semaglutide
Cloudy intermediate-acting insulin
Insulin isophane (NPH)
"Triptan sensations" - patients feel this in their chest
Pressure/tightness/heaviness
Calcineurin inhibitor applied topically for eczema
Tacrolimus
Neuraminidase inhibitor given within 48 hr of flu symptoms
Oseltamivir
Contraindicated if eGFR < 30; risk of lactic acidosis
Metformin
Peakless long-acting insulin with acidic pH
Insulin glargine
Contraindicated in hemiplegic or basilar migraine
True (absolute contraindication)
mTOR inhibitor also known as rapamycin
Sirolimus
Life-threatening zidovudine side effect requiring serial CBCs
Anemia and Neutropenia
Black-box warning for medullary thyroid cancer (rodent data)
Semaglutide
Must “roll, don’t shake” this insulin before administration
Insulin Isophane (NPH)
Cannot be used within 14 days of phentramine
MAOIs
Both tacrolimus and sirolimus require this level of blood test monitoring
IV-Only route required for herpes encephalitis
Semaglutide side effect that delays absorption of oral meds
Gastric emptying
Cannot be mixed in the same syringe with insulin glargine
Any other insulin