BIOLOGY
These 2 lab biomarkers are used to gauze heavy alcohol use over weeks.
What are carbohydrate-deficient transferrin and Phosphatidylethanol.
This MAUD requires caution due to hepatic considerations.
What is Naltrexone.
This treatment uses rewards to compete with substance induced reinforcement.
What is contingency management.
This condition presents with encephalopathy, ataxia, and ophthalmoplegia.
What is Wernicke’s Encephalopathy.
4-5 symptoms of DSM-5 criteria for Cannabis Use Disorder qualifies for this level of severity.
What is moderate severity.
This is the primary bacterial risk in endocarditis among injection drug users.
What is Staphylococcus aureus.
The “MOTHER STUDY” showed that compared to Methadone, Buprenorphine resulted in better outcomes in this condition.
What is Neonatal Abstinence Syndrome. Note: Methadone had higher pt retention.
This technique asks patients to articulate their reasons for change and resolve ambivalence.
What is "MI"
This alcohol withdrawal treatment protocol results in less medication usage and similar outcomes.
What is Symptom Triggered.
Based on NESARC, National Epidemiologic Survey of Alcohol & Related Conditions, this was largest subtype of AUD.
What is Young Adult (30%) largest group, mid 20’s, low rates co-occurring MH dxs. Low rates family AUD. Rarely seek help.
In this trimester of pregnancy, methadone maintenance doses are changed.
What is 2nd trimester methadone is increased because of increased metabolism and blood volume.
This medication has shown efficacy for cocaine use disorder and AUD.
What is topiramate (or disulfiram).
What follows in this series: Pre-contemplation, Contemplation, Preparation, Action.
What is Maintenance.
This electrolyte abnormality is a hallmark of severe alcohol withdrawal and can complicate its treatment.
What is Hypomagnesemia (associated with longer duration of DTs, seizures, arrhythmias, thiamine resistance).
This class of substances are frequently missed on immunoassay DAUs.
What are non diazepam related benzos. chlordiazepoxide & chlorazepate -they share metabolites.
The extended amygdala, hypothalamus & HPA are parts of this functional system in addiction.
What is the anti-reward system.
This class of medication is known to cause paradoxical responses in children and elderly patients.
What are benzodiazepines.
This therapeutic approach is recommended for the PTSD + SUD patient.
What is integrated therapy.
Insomnia, irritability, decreased appetite, followed by anger and depressed mood continuing for weeks is characteristic of this withdrawal syndrome.
What is cannabis withdrawal.
The American Society of Addiction Medicine defines this as level 4 of care.
What is medically managed intensive inpatient treatment.
This neuroanatomical shift moves drug taking from impulsive to compulsive behavior.
What is the shift from the ventral striatum to the dorsal striatum.
This SUD medical emergency symptom can be worsen by the use of a pure Beta blocker.
Cocaine induced angina. Propanolol & metoprolol can cause unopposed alpha stimulantion and worsen vasoconstriction.
When patients reach this milestone, they are in early remission by DSM criteria.
What is 3 months.
Among substances, this substance is the rare example of zero order kinetics.
What is alcohol. BAL drops by 0.015 mg/100 ml per hour (0.02 in some pts)
A reduction of buprenorphine dose to 8 mg BID if on more than 16mg/d.
What are perioperative dosing recommendations the day prior to surgery (others rec’ 12mg)