Diagnostic Testing
Surveillance Systems
Case Fatality & Adjustments
Bias and Study Design
Screening & Public Health
100

This measure represents the proportion of individuals with disease who test positive.


What is Sensitivity?

100

Routine reporting of diseases from hospitals and laboratories to health departments.

What is Passive Surveillance?

100

The number of new cases of disease occurring in a population during a specified time period.

What is Incidence?

100

Bias that occurs when individuals with disease remember exposures differently than those without disease.

What is Recall Bias?

100

Screening performed for an entire population regardless of risk.

What is Mass Screening?

200

This measure answers the question: “If the test is positive, what is the probability the person truly has the disease?”

What is Positive Predictive Value (PPV)?

200

Public health officials actively contacting hospitals and laboratories to identify cases.

What is Active Surveillance?

200

The total number of existing cases of disease in a population at a given time.

What is Prevalence?

200

Bias caused by inaccurate instruments or inconsistent data collection.

What is Measurement Bias?

200

Screening that occurs when patients seek care for another reason.

What is Opportunistic Screening?

300

What test measures are impacted when prevalence increases?

PPV and NPV

300

Surveillance conducted at selected reporting sites used to represent broader disease trends.

What is Sentinel Surveillance?

300

This measure reflects the proportion of diagnosed cases that result in death.

What is Case Fatality Rate (CFR)?

300

Bias occurring when earlier detection appears to increase survival time even though disease progression is unchanged.

What is Lead-Time Bias?

300

Screening that uses several tests at the same time to detect multiple diseases.

What is Multiphasic Screening?

400

A test with very high specificity is most useful for this purpose.

What is ruling in disease (SPIN)?


400

A surveillance system that tracks symptoms like fever and cough before diagnoses are confirmed.


What is Syndromic Surveillance?

400

This measure estimates the proportion of all infections, including undiagnosed cases, that result in death.

What is Infection Fatality Ratio (IFR)?

400

Bias occurs when screening detects slow-progressing disease more often than aggressive disease.

What is Length-Time Bias?

400

Screening tests should prioritize this test characteristic.

What is High Sensitivity?

500

These four measures evaluate diagnostic test performance.

What are Sensitivity, Specificity, PPV, and NPV?

500

These three attributes help evaluate surveillance systems according to CDC guidelines.

Surveillance system attributes:
--- Simplicity
--- Flexibility
--- Data quality
--- Acceptability
--- Sensitivity
--- Predictive value positive
--- Representativeness
--- Timeliness
--- Stability

500

This mortality measure reflects deaths in the entire population regardless of cause.

What is Crude Mortality Rate (CMR)?

500

Bias that occurs when study participants are not representative of the target population.

What is Selection Bias?


500

Confirmatory tests should prioritize this test characteristic.

What is High Specificity?

M
e
n
u