UTI Anti-Infectives
What body system does fluoroquinolones disrupt to kill bacteria?
Bacterial cell wall synthesis and DNA replication.
What is the prototype medication for OAB?
Oxybutynin.
What is the prototype medication for urinary retention?
Bethanechol.
What type of allergy must you assess for before administering Ciprofloxacin?
Sulfa and quinolone allergies.
What history must you check before giving Bethanechol to ensure no urinary retention obstruction?
History of urinary retention or physical obstruction.
What major tendon risk is associated with Ciprofloxacin?
Tendon rupture
What receptor does Oxybutynin block to relax the detrusor muscle?
M3 receptors.
What is the mechanism of action of Bethanechol on the bladder muscle?
Stimulates muscarinic receptors to contract the bladder muscle and restore emptying
Why must Anticholinergics be used with extreme caution in the elderly?
High toxicity risk, confusion, and Beers criteria precautions.
What vital sign or body measurement should you track regarding post-void residual volume?
Urine volume and bowel regularity.
Why must Ciprofloxacin be separated from antacids?
Antacids decrease its absorption and effectiveness.
What is a major benefit of taking Oxybutynin?
Reduces urinary urgency.
What is the mechanism of action of Bethanechol on the bladder muscle?
muscarinic receptors to contract the bladder muscle and restore emptying
What specific time relative to meals should Bethanechol be taken?
On an empty stomach.
What cognitive and bowl status should be assessed prior to administration?
Cognitive status and bowel history.
What sunlight precaution is needed?
Wear sunscreen and avoid UV exposure.
What Pt teaching tip helps manage severe dry mouth?
Suck on hard candy or chew gum.
What physical obstruction must be verified as absent before giving Bethanechol?
No physical/mechanical obstruction.
What are the primary side effects associated with Anticholinergics?
Urinary retention, constipation, blurred vision, and dry eyes.
What specific urinary leakage metric should be monitored continuously?
Track urinary leakage frequency.
What severe gastrointestinal issue must patients report immediately?
Severe diarrhea.
What specific medical conditions are absolute contraindications for taking Oxybutynin?
Uncontrolled narrow-angle glaucoma, urinary retention, or gastric retention.
What respiratory symptom or breathing change should be reported immediately?
Wheezing or chest tightness
What weather condition requires extra caution and hydration when taking anticholinergic medications?
Hot weather.
What pre-administration assessment is critical regarding voiding patterns?
Assess voiding patterns, history of urinary retention, cognitive status, and bowel history.