Background
What is the microbiome made of?
What is bacteria, viruses, and fungi?
This technology can measure the spatial patterns of microbiota
What is a Microbiome Digital Twin?
True or False: The sensor interacts directly with the analyte?
What is True?
True or False, engineered bacteria are being studied for disease detection and treatment
What is True?
What are our names?
What is Anna, Alyssa, Miryam, Makadya?
What diseases can be caused when our microbiome is out of balance?
What is CVD, IBD, Cancer, diabetes, brain disorders?
Name one type of data that can help build a microbiome digital twin (multiple answers)
What are stool samples, skin swabs, mouth swabs, genital swabs, microbial DNA sequencing, diet information, or clinical measurements?
What are the two main types of BWCBs?
What is constitutive and inductive?
What amino acid did engineered E. coli break down in the gut in patients with PKU?
What is phenylalinine?
What technology was first developed for aerospace engineering?
What is Digital Twins?
Who were the pioneers of germ theory of disease?
What is Louis Pasteur and Robert Koch?
MDTs automatically prove that a treatment/intervention will work in a real person
What is no?
For the detection of AHLs, the Lux system was integrated with the ___ reporter to produce fluorescence
What is GFP?
In patients with IBD, engineered bacteria are designed to detect ___ .
What is inflammation?
True or False: The BWCB in the assigned reading research paper, is considered to be inducible
What is False?
What are three companies that stand to profit from new research?
What is Nestle Health Science, Seres Therapeutics, Jamieson?
The long-term healthcare goal of an MDT.
What is personalized healthcare?
What are 3 advantages to BWCBs?
What is Affordable, Portable, Versatile?
Engineered E. coli Nissle could produce a molecule detectable in which bodily fluid as a potential cancer diagnostic tool?
What is urine?
In one of the pre-presentation articles, E. coli was engineered to produce what major human hormone?
What is insulin?
How can engineered bacteria detect diseases?
What is through sensing biomarkers, environmental changes and chemical signals?
Why might a MDT combine biological data with computational models?
What is to simulate or predict how a microbiome may respond to treatments/interventions?
What are the major research gaps in the current BWCB literature?
What is commercialization, standardization, genetic libraries?
Name the 4 major functions of engineered bacteria discussed today
What is Metabolize, Deliver, Sense, Target?
The second phase of the Human Microbiome Project studies under these three conditions?
What is pregnancy and preterm birth, IBD and stressors affecting those with prediabetes?