The pathogen vault
Transmission detectives
Clinical mysteries
Diagnostic challenge
One health hot seat
100

Which bacterium causes undulant fever

Brucella spp

100

What is the primary route of human infection with rabies following a dog bite?    

Inoculation of infected salivary through bite wound

100

A person develops hydrophobia and aerophobia following a dog bite. Which disease is suspected?    

Rabies

100

Which serological test is commonly used for screening brucellosis in livestock?    

Rose Bengal Plate Test

100

What are the three interconnected domains of the One Health approach?    

Human animal and environmental health

200

Which protozoan parasite causes visceral leishmaniasis and is transmitted by sandflies?    

Leishmania donovani

200

Which tick genus is the principal vector of Crimean-Congo hemorrhagic fever virus?    

Hyalomma

200

A farmer presents with an eschar and severe regional lymphadenopathy after handling infected animal tissues. Which zoonosis should be suspected?    

Cutaneous anthrax

200

Which molecular diagnostic technique is used for early detection of leptospirosis?  

PCR

200

Which animal group serves as the natural reservoir of Nipah virus?    

Pteropid fruit bats

300

Which bacterial pathogen causes Q fever and can survive in the environment as a highly resistant small-cell variant?    

Coxiella burnetii

300

Which zoonotic disease is associated with exposure to aerosolized birth fluids from infected sheep and goats?    

Q fever

300

A slaughterhouse worker develops an ulcer with a characteristic black necrotic center and surrounding edema. Which disease is classically associated with this lesion?    

Cutaneous anthrax

300

Which test is considered a reference method for demonstrating rabies antigen in brain tissue?    

Direct flourescent Antibody Test(DFA)

300

Which bacterial genus is responsible for bovine tuberculosis and includes the zoonotic species M. bovis?  

Mycobacterium 

400

Which viral family includes the causative agents of Ebola virus disease and Marburg virus disease?    

Filoviridao

400

What is the term for transmission of a pathogen from an infected animal to a human through an arthropod vector?    

Vector borne zoonotic transmission 

400

A patient develops fever, jaundice, renal dysfunction, and conjunctival suffusion following exposure to floodwater. Identify the disease.  

Leptospirosis

400

Which molecular technique can identify and compare resistance genes and transmission-related genetic similarities among bacterial isolates from humans and animals?   

Whole genome sequencing(WGS)

400

What epidemiological term describes the transmission of a pathogen from an animal reservoir into a new host species or population?  

Spillover

500

Which bacterium causes plague and is classically transmitted by infected fleas associated with rodent hosts?    

Yersinia pestis

500

Which form of transmission occurs when a vector acquires a pathogen and the pathogen multiplies within the vector before transmission to another host?  

Propagative transmission 

500

A patient develops atypical pneumonia and hepatitis following exposure to parturient sheep. Which zoonotic pathogen is the likely cause?    

Coxiella burnetii

500

Which serological test detects phase II IgG antibodies and is commonly used in diagnosing acute Q fever

Indirect immunofluorescence Assay

500

What is the term for the movement of antimicrobial resistance genes between bacteria through mechanisms such as conjugation, transformation, and transduction?    

Horizontal gene transfer


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