Molecular Interactions
Answer: A disulfide bond.
How many sigma bonds and how many pi bonds are in a double bond?
One sigma bond and one pi bond.
Which level of protein structure is the linear amino acid sequence?
Primary structure
Is H1N1 a protein, a cell, a virus, or a target receptor?
virus
what is the term for the particular cell types or tissues a virus tends to infect.
Tropism
What type of interaction occurs when nonpolar groups cluster together away from water, helping drive protein folding?
What type of orbital overlap forms a pi bond?
Sideways overlap. (other answers also accepted)
Which level of protein structure includes alpha helices and beta sheets?
Secondary structure.
What protein on the flu virus’s surface attaches it to host cells?
Hemagglutinin (HA)
what happens during the step: Assembly
Once enough viral components have been produced via the host cell, they must be assembled.
The viral genome and structural proteins are packaged into new particles. The capsid protects the genome, while other components may help the virus recognize and enter future host cells.
A fully assembled virus particle capable of initiating infection is called a virion.
Viruses do not usually reproduce by splitting into two daughter cells the way bacteria do. Instead, their components are produced separately and assembled into new particles.
What interaction occurs between a hydrogen on N or O and another electronegative atom with a lone pair, stabilizing alpha helices and beta sheets?
Answer: Hydrogen bonding.
In wedge-and-dash notation, which way does a solid wedge point?
Toward the viewer.
What functional group is a peptide bond, written as –C(=O)–NH–
An amide
The binding pocket is surrounded by the 130-loop, the 150-loop, the 220-loop, and which helix?
The 190-helix.
what does RNA-dependent RNA polymerase do and why is it importaint
synthesizes RNA from an RNA template, skips need for DNA intermediate
What type of interaction occurs between a positively charged lysine side chain and the ring of phenylalanine?
Answer: A cation-pi interaction.
What are nonsuperimposable mirror-image stereoisomers called?
Answer: Enantiomers.
What effect gives a peptide bond partial double-bond character and restricted rotation?
Resonance
Which piece of HA forms the globular head and contains the receptor binding site?
HA1
what are the two ways a virus may attach to a host cell?
A protein in the virus's capsid, the protective protein shell.
A glycoprotein embedded in the viral envelope, a membrane surrounding some viruses.
What is it called when pi electrons spread out across alternating single and double bonds, as in 1,3-butadiene?
Answer: Conjugation.
Why do cis-2-butene and trans-2-butene exist as separate isomers?
Answer: The pi bond restricts rotation around the double bond.
Hemagglutinin is made of three subunits. Which level of protein structure describes that arrangement?
Quaternary structure.
Which sialic acid linkage does the 2009 H1N1 virus prefer, the one found in the human upper airway?
α2,6
how does Negative-sense single-stranded RNA (−ssRNA) work and why?
Must first make complementary positive-sense RNA that can serve as mRNA. These viruses need an appropriate RNA-dependent RNA polymerase. Not same polarity.