Misc: Schizophrenia & Depression
Treatment of depression should be taken at least ________ weeks.
4-8 weeks
Generic for Paxil
Paroxetine
Name of olanzapine orally disintegrating tablet
Zyprexa Zydis ODT
A SSRI, may cause QT prolongation with max dose of 20mg per day orally
Citalopram (Celexa)
Major side effects of antidepressants, especially SSRIs: ________ dysfunction
Sexual
Negative signs and symptoms of schizophrenia
Loss of interest or motivation, lack of emotion (apathy), social withdrawal, lack of speech
Generic for Remeron
Mirtazepine
Name of aripiprazole IM administration every 4 weeks
Not the first-line therapy for schizophrenia. Needs to monitor ANC.
Clozaril (clozapine)
Group of side effects caused by use of antipsychotics (especially SGA), but not EPS.
Metabolic syndrome (dyslipidemia, weight gain, hyperglycemia)
Positive signs and symptoms of schizophrenia
Hallucinations, delusions, disorganized thinking/behavior
Brand for Desvenlafaxine
Pristiq
Invega Sustena (generic name & freq)
Paliperidone IM administration monthly
Mild form of depression should be treated with this type of psychotherapy: ______ behavioral therapy
Cognitive behavioral therapy (CBT)
Antidepressant class inhibits primarily NE and 5-HT reuptake. Cause anticholinergic side effects, orthostasis, risk of falls. Overdosing can cause death.
TCA: tricyclic antidepressants, especially tertiary amines (amitriptyline, doxepin)
Pharmacology (MOA) of buproprion
Dopamine and norepinephrine reuptake inhibitor
Brand for Lurasidone
Latuda
Antidepressant available as ODT. May increase appetite and help with sleep.
Mirtazapine SolTab (Remeron SolTab)
DSM-V criteria for depression diagnosis. Part of M.S.I.G.E.C.A.P.S.
Concentration - decreased
Too much serotonin causes this, which are signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures)
Serotonin syndrome
Result with use of MAO-B inhibitors when taken with other SSRIs, TCAs, SNRIs, or tyramine-rich foods
Hypertensive crisis or serotonin syndrome
Generic for Saphris
Asenapine
Antipsychotic available as patch and also given sublingually.
Asenapine (Saphris)
The IM formulation of risperidone given every 2 weeks.
Risperdal Consta
With use of antipsychotics, a medical emergency with hyperthermia, muscle rigidity, mental status changes, intense muscle contractions may lead to acute renal injury.
Neuroleptic malignant syndrome (NMS)