TERMS
Non-proprietary name which identifies the drug's active ingredient
Generic name
AST & ALT are used to measure this
Liver function (LFTs)
Role of the nurse when intervening on a patient's behalf
Advocate
Fastest parenteral route of absorption
Intravenous (IV)
Consuming grapefruit juice inhibits this
Cytochrome P-450 system
Information regarding any serious, life-threatening adverse effect
Black Box Warning
Hypersensitivity to a drug
Allergic reaction
BUN is the abbreviation
Blood urea nitrogen
Actual or potential problems requiring intervention by the nurse
Nursing diagnosis
Administering medications through a nasogastric (NG) tube is an example of this route
Enteral
Drug with a 1/2 life of 2 hours and current serum level of 20mg/dL will take this long to reach 5mg/dL
4 hours
Jaundice and elevated liver enzymes in response to a drug indicates this
Hepatotoxicity
Response which occurs when an individual reacts in a unique manner to a drug that is not usual or predicted
Idiosyncratic response
Serum level specific to renal function
Creatinine
Comparing the desired outcome with the actual outcome
Evaluation
These drugs easily penetrate cell walls and are more likely to cross the blood-brain barrier
Lipid soluble
Two unlike drugs together create a greater effect than either alone (1+1=3)
Synergistic effect
Significant rise in BUN & creatinine after drug administration most likely indicates this
Nephrotoxicity
Measure of the extent of drug absorption for a given drug & route
Bioavailability
Value included in the CBC which indicates oxygen-carrying capability
Hemoglobin (Hgb)
Labs and diagnostic tests are part of this phase of the nursing process
Assessment
Result of first-pass effect
Little to no active drug sent to general circulation
One drug blocks the effect of the other
Antagonistic effect
Bone marrow suppression as a result of drug administration
Blood dyscrasia
Condition under which a drug should not be used
Contraindication
Used to monitor warfarin (Coumadin) therapy and also used to look at potential liver damage
PT/INR
Two of the four criteria which must be included when setting goals/outcomes for a patient
Specific
Measurable
Realistic
Time-framed
If a highly protein-bound drug is given to a patient with an albumin of 1.6, this may result.
Drug toxicity
Maintenance of desired drug level (in=out)
Steady state
Characterized by difficulty breathing, increased HR, panic, and low BP
Anaphylaxis