Transporters
The Na+/K+ ATPase is located on the ________ membrane of the PCT, Thick Acending LOH, DCT, and Collecting Duct
What is the Basolateral Membrane?
Potassium handling in the collecting duct is controlled by this hormone.
What is aldosterone?
This hypertension drug acts on mineralocorticoid receptors and may cause hyperkalemia and frequent gynecomastia
What is spironolactone?
The majority of potassium is reabsorbed in which part of the nephrone?
What is the proximal convoluted tubule?
The positive lumen potential created by the ________ transporter in the thick ascending limb allows for Mg2+ reabsorption
What is ROMK?
The side effects caused by a Loop diuretic is analogous to the LOF mutation seen in which genetic disorder?
What is Bartter Syndrome?
Ingestion of this candy/food may precipitate hyperkalemia even with low aldosterone levels
What is licorice?
The negative lumen potential created by the reabsorption of _______ allows for K+ excretion in principal cells
Potassium reabsorption in the PCT is primarily _______ (trans/paracellular) due to being pulled with water, a process called ____________
What is paracellular, solvent drag?
Resistance to this hormone makes patients with Type II Diabetes more prone to hyperkalemia
What is Insulin?
Which two genetic mutations effect the NCC (Na+/Cl-) channel in the DCT but have opposite effects on serum potassium?
What is Gitelman's Syndrome (hypokalemia) and Gordon's Syndrome (hyperkalemia)?
Potassium is reabsorbed in alpha-intercalated cells through which antiporter?
What is the H+, K+ ATPase?