B
What is the best course of action when glass fragments are observed in blood bank test tubes?
Don't use them
What is the root cause of most fatal transfusion reactions?
Clerical errors
Iron Overload is categorized as what transfusion reaction type?
Delayed nonimmunologic transfusion reaction
Which of the following best describes the actions of infusion personnel if a transfusion reaction is suspected?
Discontinue the transfusion and notify the blood bank
Passive infusion of non-group ABO antibodies from platelet transfusions can result in what type of ABO discrepancy?
Group I Discrepancies in the Reverse Typing
What is the best course of action regarding a cloudy reagent?
Do not use the reagent. It may be contaminated
What is the best resolution to the problem of Wharton's jelly interference for ABO testing?
Wash x4
Which of the following component is most often responsible for bacterial contamination?
Who do you notify when a blood component's safety and purity is found to compromised by bacterial contamination or hemolysis?
Blood donor facility (Versiti or American Red Cross)
What is the proposed resolution when rouleaux is suspected in an ABO discrepancy?
Use the saline replacement technique
What type of transfusion reaction is the only reaction that can potentially be restarted?
Urticarial Reactions
Why do neonates often have an ABO discrepancy.
Neonates do not produce anti-A and anti-B for four to six months. Perform ABO forward typing only.
Fatalities that occur as a direct result of a blood transfusion must be reported to:
FDA
Asymptomatic hemoglobinuria is the most common initial symptom of what transfusion reaction type?
Hemolysis due to physical or chemical means
A room temperature reactive alloantibody, such as anti-M, can result in what type of ABO discrepancy?
Unexpected antibody reactions
What will the post-transfusion DAT result be in an
Acute Hemolytic Transfusion Reaction
Positive
What is normally performed in the initial transfusion reaction work up?
Visual inspection for free hemoglobin in post reaction blood sample, Clerical check, Direct antiglobulin test
What blood product is indicated in the treatment of Coumadin over-administration?
Fresh frozen plasma
What antibody is often implicated in cases of delayed hemolytic transfusion reactions?
Anti-Jka
A patient is suspected of having passively acquired antibodies from a different ABO group PLT transfusion that are causing an ABO discrepancy. What is the best course of action to resolve the problem?
Perform a complete patient history to determine any recent transfusions
How is cytomegalovirus (CMV) transmitted through infusion?
From infected WBC in product
What is the leading indication for red blood cell transfusion?
Increased oxygen-carrying capacity in anemic patients
Anti-A 4+
Anti-B 4+
A1 Cells 1+
B Cells 0
Given the above results, determine the MOST likely cause(s) of the following ABO discrepancy?
Elderly patient reverse not reacting/not reacting strongly
Anti-A 4+
Anti-B 0
Anti-A1 0
A1 Cells 2+
A2 Cells 0
B Cells 4+
Given the following results, determine the MOST likely cause(s) of the following ABO discrepancy?
An A2 with anti-A1
Wharton's jelly has been implied in many ABO discrepancies. Wharton's jelly interference is classified under which category of ABO discrepancies?
Group III Plasma or Protein Abnormalities