Genesis: Into the Roots
Cellcyclopedia
GI Hall of Fame:Guess who?
Know your scope!
Gut check:What's news?
100

The term combines Latin roots, meaning “worm-shaped,” and “an attachment" respectively.



What is vermiform appendix?

100

These specialized epithelial cells in the intestine secrete mucus to protect and lubricate the intestinal lining while supporting immune function.

What is goblet cell?


100

This Russian scientist's experiment on dogs helped explain how the nervous system influences digestion and led to the concept of conditioned reflexes.


Who is Ivan Pavlov?


100

This is the length (in cm) of a pediatric upper endoscope and colonoscope respectively.

What is ~110 cm and 168 cm?

100

These partially digested fragments of gluten, resistant to complete breakdown in the GI tract, can trigger an immune response in patients with celiac disease and can be detected in urine or stool.

What are gluten immunopeptides?

200

This part of GI tract combines two roots meaning "to carry," and "I ate “.

What is esophagus?

200

These exocrine cells located deep within the gastric glands/oxyntic glands secrete pepsinogen and gastric lipase.

What is peptic cell, chief cell or zymogen cell?


200

This condition is named after a gastroenterologist at Mount Sinai Hospital, who published his findings in the Journal of the American Medical Association under the title “Regional Ileitis: A Pathologic and Clinical Entity. 

What are Brunner's glands?

200

This is the commonly recommended concentration of diluted epinephrine (in saline) used for endoscopic injection to control non-variceal upper GI bleeding.

What is 1:10,000 ?

200

Thi is the first and only FDA‑approved potassium‑competitive acid blocker (PCAB) for the treatment of gastroesophageal reflux disease (GERD) in adults.

What is VOQUEZNA® (vonoprazan) ?

300

The GI term comes from a Medieval Latin root, meaning “space of twelve digits".

What is duodenum?

300

These secretory cells located at the base of the crypts of Lieberkühn in the small intestine, particularly in the ileum, secrete anti-microbial peptides and also growth factors that support intestinal stem cell maintenance and proliferation.

What is paneth cell?

300

hese glands were described by a Swiss anatomist/ physiologist and secrete bicarbonate rich fluid in the duodenum.


What is Crohn's disease?


300

This is the outer diameter range (in mm) of a pediatric upper endoscope.

What is  ~ 9mm?

300

This oral small molecule and selective sphingosine 1-phosphate (S1P) receptor 1 and 5 modulator approved for the treatment of patients with moderately to severely active UC.

What is ozanimod?

400

This disease originates from the Greek word "koiliakos," meaning "abdominal"/ translates to 'disease of the bowel'?

What is celiac disease?

400

These specialized endocrine cells located within the islets of Langerhans in the pancreas, synthesize and secrete somatostatin.

What are Delta cells (or δ-cells)?

400

These two scientists won the 2005 Nobel Prize in Physiology or Medicine for discovering Helicobacter pylori and its role in causing peptic ulcer disease.

Who are Barry Marshall and Robin Warren?

400

This is the outer diameter range (in mm) of a neonatal upper endoscope?

What is 5 mm?

400

This first-of-its-kind oral microbiota-based therapy was FDA-approved in 2023 to help prevent recurrent Clostridioides difficile infection by restoring gut microbial balance.

What is Vowst?

500

This GI term originates from a Greek word meaning "poppy juice," and was later adopted into Latin.

What is meconium?

500

These cells are specialized macrophages that act as the primary immune defense within the liver.

What are Kupffer cells?

500

This British GI physician renowned as the ' mother of hepatology" authored the landmark textbook ' Diseases of the Liver and Biliary System' and founded the liver unit at the Royal Free Hospital in London.  

Who is Sheila Sherlock?

500

The shaft of the endoscope is made of these polymers due to their flexibility, biocompatibility, and resistance to abrasion.

What is poly urethane and poly amide?

500

This first-in-class inhibitor of the sodium/hydrogen exchanger 3 (NHE3) in the gut is used to treat IBS-C

What is tenaponor?

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