General Characteristics
Genetic material of Picarnoviridae Family
single-stranded positive-sense RNA viruses
Replication of picornaviruses occurs in this part of the cell.
cytoplasm
This picornavirus causes the common cold.
rhinovirus
Coxsackieviruses were first isolated in this U.S. town, which also lent the virus its name.
Coxsackie, New York
This inactivated vaccine is used against poliovirus.
Salk vaccine
This virus in the Picornaviridae family causes poliomyelitis.
poliovirus
These cellular structures participate in assembling viral particles.
endoplasmic reticulum and membranes
The capital of Brazil?
Brazilia
This method is used to detect viral antigens in samples.
ELISA (enzyme-linked immunosorbent assay)
This hygiene measure helps prevent the fecal-oral transmission of picornaviruses.
handwashing
Name three primary genera of picornaviruses that cause diseases in humans
Enterovirus, Hepatovirus, and Rhinovirus
This viral enzyme is essential for RNA synthesis from an RNA template.
RNA-dependent RNA polymerase
Enteroviruses often cause aseptic meningitis and this childhood illness known as “hand, foot, and mouth disease.”
enteroviral stomatitis
This diagnostic test detects the presence of viral RNA in cerebrospinal fluid, blood, or throat swabs, making it the gold standard for identifying Echovirus and Coxsackievirus infections.
What is PCR (polymerase chain reaction)?
PCR (polymerase chain reaction)
surprise
300 points
2*2:2=?
2
After initial replication, poliovirus spreads through the bloodstream to this part of the nervous system, where it causes motor neuron damage.
spinal cord (especially the anterior horn)
Name the primary transmission route of picornaviruses like poliovirus.
ecal-oral route
ooopppss
minus 400p
Name the two main types of vaccines against poliovirus.
oral polio vaccine (OPV) and inactivated polio vaccine (IPV)
This is the main structure of the picornavirus capsid that protects its genome.
icosahedral capsid
After entering the body, Echoviruses replicate in this lymphoid tissue before spreading to other organs.
Peyer’s patches in the small intestine
This severe complication of poliomyelitis occurs due to motor neuron damage.
paralysis
This type of cell culture is commonly used to grow and study picornaviruses.
What are HeLa cells
Coxsackievirus is divided into two groups:
Group A, associated with diseases like hand, foot, and mouth disease, and Group B, which can cause this severe complication affecting the heart myocarditis