Non-sterile Compounding Specifics
The process of grinding a substance into a fine powder through trituration in a mortar and pestle or spatulation on an ointment slab to reduce the particle size with a minimal amount of a liquid.
What is levigation?
A technique of adding a diluent to a powdered medication to prepare a drug product.
What is reconstitution?
The abbreviation for bioavailability.
What is F?
A supplemental label that is included with a prescription on the patient label or directly on the product container and emphasizes key information that a patient or caregiver of a patient needs to know about the prescription.
What is an auxiliary label?
A calculation component that could have the consequence of a ten-fold dose increase.
What is a trailing zero?
A technique of combining two or more substances with varying quantities together in order to create a homogenous mixture by mixing the ingredient with greater quantity into the ingredient with lesser quantity.
What is geometric dilution?
The description of a compounded product being free of contamination and microbial organisms.
What is sterility?
The terminology used to describe the maximum concentration of a given dose.
What is CMax?
Documentation specific to each prescription.
What is a prescription (Rx) number?
The information about the dispensing pharmacy that is required on an outpatient prescription label.
What is the name, address and phone number?
A technique which utilizes a mortar and pestle to grind a solid, reducing its particle size into a fine powder.
What is trituration?
A class of drug that has been shown in studies on animals and or humans that may have the potential to cause cancer, development or reproductive toxicity, or harm to organs if exposed to them.
What is a hazardous drug?
What a drug does to the body.
What is pharmacodynamics?
The extent to which the product retains its physical and chemical properties through the product’s beyond-use date.
What is stability?
The process of ensuring a prescription or order is valid and includes all legal and necessary components.
What is verification?
The BUD and storage for a water-containing oral compounded preparation with a water activity aw ≥ 0.60
What is 14 days refrigerated?
The rate at which a medication should be administered.
What is flow rate?
What the body does to a drug.
What is pharmacokinetics?
Documentation that includes all necessary information and appropriate procedures to safely compound a specific preparation.
What is a master formulation?
The final step of checking a product or final preparation against the prescription.
What is certification?
Abbreviation for “add a sufficient quantity to make”.
What is qs ad?
A type of intravenous infusion where a medication is diluted into a small volume of IV solution and administered through a primary infusion line.
What is a piggyback?
The result or outcome of calculating the clearance divided by volume (CL / V).
What is Ke?
Documentation generated every time a preparation is compounded with a prescription, including specific information that must be verified before it is dispensed.
What is a compounding record?
The process of reviewing a dispensed prescription against the original prescription and information documented within 72 hours of certification.
What is quality assurance?