Weeks 1&2
Weeks 3&4
Weeks 5&6
Week 7
Week 8
100
Ototoxicity of ahminoglycosides can cause what kind of irreversible damage (2)?

What are vestibular and cochlear damage?

(Week 2 Anki)

100

What is the primary immune mediator of Type 1 hypersensitivity reactions?

What is IgE?

(Week 3 Anki)

100

How many FADH2 are produced by the TCA cycle per acetyl-CoA?

One!


(Week 6 Anki)

100

This type of collagen makes up scar tissue and dermis

What is Type 1?

(Week 7 Anki)

100

This laboratory technique is used for specific localization of genes and direct visualization of chromosomal anomalies

What is Fluorescence in situ hybridization (FISH)?

(Week 8 Anki)

200

This is the only immunoglobulin that can be secreted in response to thymus-independent antigens

What is IgM? 

(Week 2 Anki)

200

This mediterranean food may be a source of oxidative stress in patients with G6PD deficiency

What are Fava beans?

(Week 4 Anki)

200

Duodenal atresia is associated with what congenital disability?

What is Down syndrome?

(Week 6 Anki)

200

How soon after birth do symptoms of fructose metabolism disorders present?

When exclusive breastfeeding ends

(Week 7 Anki)

200

If two linked genes have a recombination frequency of 12%, approximately how far apart are they?

What is 12 centiMorgans (cM)?

(Week 8 Anki)

300

A patient presents with a pigmented, scaly skin rash in the molar distribution of his face, neck and back of hands. It has been present for months and is worse after sun exposure. What nutrient is he likely deficient in?

What is vitamin B3?

(Q:12276)

300
How does Protein A act as a virulence factor of Staphylococcus aureus?

Binds Fc region of antibody, preventing IgG mediated phagocytosis

(Week 3 Anki)

300

What compartment is the majority of a drug with low Vd found in?

What is intravascular (e.g., plasma)?

(week 5 Anki)

300

Characterized by fatty liver, abdominal distention, and edema this malnutrition disorder results from a protein deficient diet.

What is Kwashiorkor?

(Anki week 7)

300

A patient shows deficient phosphorylation of mannose residues on certain glycoproteins in the Golgi apparatus. In unaffected patients, these proteins are normally transported to what cellular location?

What is a Lysosome? 

(Q: 11930)

400
Malignant epithelial cells in the sigmoid colon have decreased their surface expression of MHC class I antigen. Which immune effector cell type is most likely to kill the transformed epithelial cells?

What are natural killer cells?

(Q:745)

400

A patient undergoing chemotherapy for non-Hodgkin lymphoma is treated with vincristine as part of his regimen. What dose-limiting adverse effect of this therapy should you warn the patient about?

What is peripheral finger numbness and tingling (peripheral neuropathy)?

(Q: 1894)

400

This medication, commonly prescribed to treat GERD, inhibits primary active transport. (Class and Example)

What is a Proton Pump Inhibitor (Omeprazole)?

400

Arterial blood gas from an unresponsive type 2 diabetic patient with mildly dry mucous membrane reveals the following. What is the most likely acid-base status in this patient?

pH: 7.22, PaCO2: 60 mm Hg, HCO3-: 24mEq/L


What is uncompensated respiratory acidosis? 

(Q: 1357)

400

After finding a lump in her breast, a 28-year-old woman is diagnosed with breast cancer. Her mother died at 34 from ovarian cancer and her maternal aunt died at 32 from breast cancer. What inherited gene mutation likely caused this cancer and what process is this gene normally responsible for?

What is BRCA1/2, DNA repair?

(Q:1083)

500
Physical examination of a forearm laceration shows erythema surrounding the wound site and yellow pus when pressure is applied. What interleuken is most likely responsible for causing accumulation of pus over this patient's wound?

What is IL-8? 

(Q: 8539)

500

Follow up for a patient being treated with combination chemotherapy for a hard mass on his next shows that it has shrunken in size and biopsy demonstrates many shrunken eosinophilic cells within the tumor. What hemeprotein released from the mitochondria most likely triggered the observed cellular change?

What is Cytochrome C? 

(Q: 297)

500

What key histological finding would to expect to see to confirm squamous cell carcinoma of the esophagus in a biopsy?

What are keratin pearls and intercellular bridges? (Q: 14878)

500

A woman with acute appendicitis has not eaten in 30 hours due to severe abdominal pain. It is suspected that this patient is utilizing ketone bodies as a significant reserve of energy due to borderline low serum glucose and moderate ketone in urine. Which tissue cannot use this energy source?

What are erythrocytes?

(Q: 1887)


500

A 23-year-old man with progressive muscle weakness, progressive vision and hearing impairment, and myoclonic epilepsy since adolescence is shown to have red muscle fibers with irregular, blotchy margins on a muscle biopsy with modified trichrome staining. Assuming an unaffected partner, what is the probability this patients passes his condition to an offspring. 

What is 0%?

(Q:357)

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