Cranial Nerves
Neurotransmitters
Lobes of the brain
Brain (midsagittal view)
Mini Cases
100

Associated with smell -- the first cranial nerve

Olfactory

100
Norepinephrine

NE

Wakefulness/arousal, sensory info from environment, fight or flight, heart rate, prepare muscles, release energy from fat storage

Depression, panic, fear, anxiety

100

Primary integration of somatosensory inputs; somatosensation; integration of somatosensory input w/ visual and auditory inputs; perception

Parietal Lobe

100

Pair of small rounded nuclei on the ventral aspect of the brain

Episodic memory, consolidating emotions, regulating reward behaviors

Mammillary Body

100

A 50-year-old man reports he can’t smell his morning coffee after a head injury. On exam, taste and vision are normal.

What is cranial nerve I (olfactory)?

200

This cranial nerve controls the muscles of the tongue

What is Hypoglossal

200

Serotonin


5-HI


Sleep, emotional control, pain regulation, emesis, carb-feeding, behaviors

OCD, Depression

200

Audition (hearing); language comprehension; support in development of long-term memory

Warnicke's area

Temporal Lobe

200
Most inferior end of brainstem


Contains life support center

Medulla

200

A patient presents with drooping eyelid, dilated pupil, and eye that is deviated "down and out."

What is cranial nerve III (oculomotor)?

300

Taste on anterior tongue, muscles on facial expression, eyelid closing

Facial
300

Gamma-Aminobutyric Acid

GABA


Major inhibitory; calms the brain (acts as a "brake" on neurotransmitters that cause anxiety)

Anxiety, panic attacks

300

Occipital Lobe

Interpretation of incoming visual information

Dorsal and ventral streams

300

Hippocampus

Pair of arch-shaped fibers that begin in the uncus and wrap around to the mammillary bodies.

Relay system for messages generated by the limbic system

300

A woman complains of facial droop on the right, inability to close her right eye, and loss of taste on the anterior 2/3 of her tongue.

What is cranial nerve VII (facial)?

400

Name and describe cranial nerve 10

Sensory - palette and epiglottis

Motor - heart, lung, esophagus, GI tract, muscle of larynx, upper esophagus, swallowing, and speaking

400

Dopamine

DA

Motor system, cognition, motivation/reward

Schizophrenia

400

Olfactory bulb and tract

Structure in the forebrain that contains small receptors, processes smell and sends it to the other brain areas for interpretation

400

After a tonsillectomy, a patient has difficulty swallowing and their uvula deviates away from the injured side.

What is cranial nerve X (vagus)?

500

What are the names of the cranial nerves in order?

Olfactory, Optic, Oculomotor, Trochlear, Trigeminal, Abducens, Facial, Vestibulocochlear, Glossopharyngeal, Vagus, Accessory, Hypoglossal

500

ACh

CNS: regulates the ANS (heartbeat) and acts as an inhibitory neurotransmitter

PNS: controls muscle action at the neuromuscular junction (excitatory)

Alzheimers, Myasthenia Gravis

500

Frontal Lobe

Mediation of higher cognitive functions such as planning (ideation), decision-making, working memory, and regulating behavior; motor planning; initiation of voluntary movements of specific body parts (motor homunculus); and motor movement for speech production

Prefrontal cortex, premotor cortex, supplementary motor area, Broca's area

500

Thalamus

Constellation of paired nuclei that relay all but one sensation to the cerebral cortex and is a critical strucutre in the motor feedback loop

500

A patient cannot shrug their shoulders or turn their head against resistance on the left. The weakness is most noticeable in the trapezius and sternocleidomastoid.

What is cranial nerve XI (accessory)?

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