Apps & Devices
The smartphone application being used in both the Hi-frequency Study and BU COVID-19 Brain Health Study.
DANA (DANA Brain Vital, DANA Modular)
Mobile and wearable devices offer an excellent opportunity to detect neurodegenerative diseases by comparing the digital data they collect to traditional biomarkers such as blood and neuroimaging.
Although Rhoda was initially reprimanded by the research community for using this term to describe this kind of digital data, it is now widely used in the context for Alzheimer’s Disease Dementia.
Digital Biomarkers
This study will look at the neurocognitive effects of COVID-19 using a smartphone application.
BU COVID-19 Brain Health Study (BU COVID)
Eligible participants must sign this form before joining a study.
Informed Consent Form (ICF)
This secure network drive is where all of our data is stored. Just don’t get too eager to access it, it might take a while.
Y-Drive
This smartphone application integrates the tests and features of many other applications, enabling participants to need just one account login to access a variety of assessments.
This approach to health care identifies unique risks and interventions for each individual patient. Rhoda believes this approach will drive down costs and increase health quality, which is why it’s a part of who we are.
Precision Medicine (Precision, precision health, precision approach. etc.)
This pilot study aims to develop and validate speech-based biomarkers for AD screening, detection, prediction, diagnosis, and monitoring.
Alzheimer’s Disease Detection through Speech Assessment (ADDF)
This federal law was passed in 1996 to set national standards to protect sensitive patient health information from being disclosed without the patient’s consent or knowledge.
Health Insurance Portability and Accountability Act of 1996 (HIPAA)
This longitudinal study began in 1948 and was initially focused exclusively on cardiovascular disease. Cognitive testing was introduced in 1976, and their brain related research has served as the foundation for this lab.
The Framingham Heart Study (Framinham, FHS)
This device is a headband that tracks patterns and quality of sleep.
DREEM Headband
Pioneered by Edith Kaplan in the 1980s, this approach emphasizes the analysis of errors during neuropsychological testing.
Boston Process Approach (BPA)
This project does not include any data collection and instead will focus on data analytics and machine learning techniques.
Discovery and Validation of Digital Biomarkers (AHA Project 3)
Participants need to give consent verbally to this agreement before determining whether they are eligible for a study.
Brief Screening Agreement
The electronic platform that the BUMC IRB uses to approve clinical studies.
Inspir
CheckMe Ring/Sleepimage is a wearable wrist and thumb ring that is worn during sleep to collect one of these vital signs.
Oxygen level, heart rate, or body temperature (any of the 3)
Smartphones are an excellent tool to conduct this type of cognitive assessment, which includes repeatedly sampling a subjects' behaviors and experiences in real time, in their natural environments.
Ecological Momentary Assessment (EMA)
The participant schedule for the Hi-Frequency Study includes this many segments.
4 segments
Vijaya Kolachalama is an expert in applying this type of computer algorithms that improve automatically through experience and by the use of data.
Machine Learning
This PBHI lab member’s favorite hobbies include hiking with their dog, skiing with their dog, talking about their dog, and talking to their dog.
Kieffer Christianson
Neurametrix is a passive data collection application that analyzes typing to determine cognitive function. Participants must have this device in order to use this application for AHA P1.
Personal Computer
Jeff Kaye (Oregon Health Science University / ORCATECH) and colleagues describe how this approach can be used to collect real-world evidence in clinical trials in dementia.
Nonintrusive sensor-based information and communication technology (ICT)
The minimum age that participants need to be in order to be eligible for the AHA P1, Hi-Frequency Study, & ADDF study.
40
This neurocognitive disorder includes memory and non-memory impairments and typically occurs as a transition stage between normal aging and dementia.
Mild Cognitive Impairment (MCI)
Amazon gift cards have been by far the most popular gift card offered for the high-frequency study. This other gift card is also offered, but is not so popular.
Dunkin