Antihistamines
what are the two types of antihistamines and what are the prototype drugs
first gen (sedating) second gen (non sedating) diphenhydramine cetirizine
prototype drug for sympathomimetics
phenylephrine
2 prototype drugs
codeine, dextromephoran
prototype drug
guaifenesin
prototype
acetylcysteine
differentiate between first and second gen antihistamines
first gen bind to central and peripheral h receptors and second gen bind only to peripheral
how do sympathomimetics work
vasoconstriction that lessens congestion
how do antitussives work
depress medulla/ cough center
how do they work
thin mucus by secreting more to lower viscosity and thus loosen secretion to make cough more productive
how it works
directly thins mucus
what are two uses for antihistamines
rhinitis, alleries/allergic rxn
who needs to use with caution
what do they treat
non productive cough
administration
oral tablet
treats:
trach care, CF, atelactasis
CNS effects of antihistamines
drowsiness/sedation, impaired coordination
topical rxn
nasal burning stinging and dryness
use caution with who
persistent cough or a cough with
excessive secretions, a high fever, persistent
headache, and nausea and vomiting
treats what overdose
acetaminophen
effects of large doses of antihistamines
hyperthermia, tachycardia, blurry vision, constipation, urinary retention
oral adr
tachy, N/V, blurred vision
dont combine with what?
antihistamine