NMS is caused by a blockade of these receptors found in the hypothalamus, nigrostriatal pathway, and spinal cord.
What is the D2 receptor?
Significant exposure to VZV is defined as this.
What is >1 hour of indoor contact or direct contact with lesions?
Spinal dysraphism is an umbrella term for a spectrum of this kind of defect.
What is a neural tube defect?
In a healthy adult, this Gram positive diplococci is the most common cause of pneumonia.
What is S. pneumoniae?
MG is diagnosed by the presence of autoantibodies to this NMJ structure.
What are postsynaptic nicotinic ACh receptors?
The mnemonic "FEVER" was made for remembering these symptoms of NMS.
Fever (>104)
Encephalopathy
Vitals unstable
Elevated CPK
Rigidity (lead-pipe)
A patient is defined as immune to VZV if they meet 1 of these 3 criteria.
1. Documented 2 doses of the VZV vaccine
2. Hx of prior VZV infection
3. Positive VZV IgG serology
Myelomeningoceles are the most severe form of spinal dysraphism, and are associated with this condition.
What is Chiari II malformation?
This Gram positive coccus in chains is the most common cause of pneumonia in neonates.
What is GBS?
LEMS is diagnosed by the presence of autoantibodies to this NMJ structure.
What are presynaptic voltage-gated Ca channels?
This acid-base disturbance is seen in patients with NMS.
What is a metabolic acidosis?
This is the guideline for VZV prophylaxis in a healthy, immunocompetent patient.
What is VZV vaccine w/in 3-5 days?
This spinal dysraphism classically presents with a sacral dimple and tuft of hair.
What is spina bifida occulta?
This Gram negative rod classically causes pneumonia in patients with CF.
What is P. aeruginosa?
Botulism exhibits its effects by this mechanism.
What is inhibiting presynaptic ACh release by cleaving SNARE proteins?
Absence of this classic symptom differentiates NMS from serotonin syndrome.
What is hyperreflexia/clonus?
This is the guideline for VZV prophylaxis for a pregnant patient.
What is VZIG w/in 10 days?
This is the #1 risk factor for developing spinal dysraphism.
What is a folate deficiency?
This Gram negative coccobacillus is the most common cause of pneumonia in patients with COPD.
What is H. influenzae?
This NMJ disorder classically improves with use of the muscle.
What is LEMS?
This medication is used to treat muscle rigidity seen in NMS.
What is dantrolene?
A CD4 count less than this number is a contraindication to the VZV vaccine.
What is 200?
This common complication of spinal dysraphism requires a consult to urology.
What is neurogenic bladder?
This Gram negative rod should come to mind when a question mentions a patient with pneumonia after going on a cruise.
What is L. pneumophila?
A patient with MG would benefit from treatment with this medication.
What is pyridostigmine?