Meds
Side Effects - Agranulocytosis, EPS, NMS, orthostatic hypotension, weight gain
Chlorpromazine(Thorazine)
Side effects - Hypertensive crisis, Serotonin syndrome
teachings - avoid tyramine
MAOI's (isocarboxazid, tranylcypromine)
report breast tenderness, irregular menstruation
Risperidone(Risperdal)
Side effects - hyperglycemia, hyperlipidemia, QT prolongation, arrythmias, hepatoxic, NMS, EPS, Orthostatic hypotension, Polyphagia
Olanzapine(Zyprexa)
Side Effects - QT prolongation, NMS, EPS, hypotension
Increased risk for death in elders
Haldol
Side effects - serotonin syndrome, increased sweating, insomnia
Contraindications - MAOI's NSAIDS
Do not stop abruptly
SSRI (citalopram, escitalopram, paroxetine)
Therapeutic range - 50-100
Side effects - Thrombocytopenia, pancreatitis, hepatoxic, N/V/D, weight gain
valporic acid (depakote)
Side Effects - Qt prolongation, arrythmias, tachycardia
contraindications - Narrow angle-glaucoma
can overdose (chest pain, seizures)
amitriptyline
Side effects - HTN, serotonin syndrome, discontinue syndrome
contraindications - Uncontrolled HTN
Do not stop abruptly
SNRI's (duloxetine, venlafaxine)
What foods are high in tyramine?
Aged cheese, deli meat, wine/alcohol, chocolate
Therapeutic range - 0.6 - 1.2
side effects - toxicity (ataxia, slurred speech, kidney failure, seizures), renal toxicity, hypothyroidism, hyponatremia, hypokalemia
Teach - 1-3L water per day, maintain salt intake
Lithium
Side effects - Respiratory depression, dependance Don't stop abruptly
Lorazepam(Ativan)
Side effects - Respiratory depressions, Ataxia, hypotension, dependance
don't stop abruptly
diazepam(Valium)
Side effects - hyperglycemia, hyperlipidemia, QT prolongation, arrythmias, hepatoxic
Don't stop abruptly
Quetiapine(seroquel)
Side effects - seizures, HTN, agitation, visual disturbances
Contraindications - Alcohol withdrawal, do not give within 14 days after stopping MAOI's
do not stop aburptly, increased risk of seizures when given in eating disorders
Bupropion